Atorvastatin

Atorvastatin Uses

Atorvastatin is used for Control Cholesterol Levels

How Atorvastatin Works

Atorvastatin reduces plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and by increasing the number of LDL receptors on liver cells to enhance LDL uptake and breakdown.

Common side effects of Atorvastatin

Headache, Altered Refraction, Dry Eyes, Dry Mouth, Glaucoma, Glossitis, Hearing Loss, Lip Swelling, Loss of Taste, Constipation, Diarrhea, Duodenal or Stomach Ulcers

Interaction

Drug : amlodipine, cimetidine, clarithromycin, diltiazem, erythromycin, itraconazole, ritonavir with saquinavir: Increased atorvastatin level.

antacid, colestipol, efavirenz, rifampin: Possibly decreased blood atorvastatin level azole antifungals, clarithromycin, cyclosporine, erythromycin, fibric acid derivatives, lopinavir with ritonavir, niacin at dosage used for lipid modification, nicotinic acid, ritonavir with saquinavir: Increased risk of severe myopathy or rhabdomyolysis. cyclosporine: Increased atorvastatin bioavailability and risk of adverse reactions.

digoxin: Possibly increased blood digoxin level, causing toxicity.

oral contraceptives such as ethinyl estradiol and norethindrone: Increased hormone level.

Food : grapefruit juice more than 1.2 L daily: Increased blood atorvastatin level.

ZOTEZO IN THE NEWS

...