Diazepam

Diazepam Uses

Diazepam is used for Anxiety, Acute Alcohol Withdrawal

How Diazepam Works

Diazepam works by acting on receptors in the brain called GABA receptors. This causes the release of a neurotransmitter called GABA in the brain.

Common side effects of Diazepam

Dizziness, Drowsiness, Fatigue, Headache, Insomnia, Lethargy, Lightheadedness, Blurred Vision, Dry Mouth, Constipation, Diarrhea, Elevated Liver Enzymes, Jaundice, Nausea, Vomiting

Interaction

Drug : antacids: Altered rate of diazepam absorption.

anticonvulsants: Decreased effectiveness of these drugs.

cimetidine, disulfiram, fluoxetine, fluvoxamine, isoniazid, itraconazole, ketoconazole, metoprolol, omeprazole, oral contraceptives, propoxyphene, propranolol, valproic acid: Decreased diazepam metabolism, increased blood level and risk of adverse effects.

CNS depressants: Increased CNS depression.

digoxin: Increased serum digoxin level and risk of digitalis toxicity.

levodopa: Decreased antidyskinetic effect of levodopa.

phenytoin: Decreased metabolic elimination of phenytoin, increased risk of adverse reactions.

probenecid: Faster onset or more prolonged effects of diazepam.

ranitidine: Delayed elimination and increased blood level of diazepam.

rifampin: Decreased blood diazepam level.

theophyllines: Antagonized sedative effect of diazepam.

Activity : alcohol use: Increased CNS depression.

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