Metoprolol

Metoprolol Uses

Metoprolol is used for Hypertension, Heart Attacks, Kidney Problems, Chest Pain, Improve Survival after a Heart Attack

How Metoprolol Works

Metoprolol is a selective beta blocker that selectively blocks beta receptors, decreases cardiac output, peripheral resistance and cardiac oxygen consumption; and depresses renin secretion.

Common side effects of Metoprolol

Fatigue, Dizziness, Depression, Nightmares, Short-Term Memory Loss, Hypotension, Headache, Insomnia, Mental Confusion, Bradycardia, Edema, Palpitations, Diarrhea, Constipation, Heartburn, Nausea, Dry Mouth, Flatulence, Gastric Pain

Interaction

Drug Amiodarone: May increase bradycardic effects. Monitor therapy.

Barbiturates: May reduce metoprolol effect. Monitor therapy.

Calcium channel blockers: May increase hypotensive effects. Monitor therapy.

Cardiac glycosides: May cause excessive bradycardia and increased depressant effect on myocardium. Use together cautiously.

Catecholamine-depleting drugs (MAO inhibitors, reserpine): May have additive effect. Monitor patient for hypotension and bradycardia.

Fluoxetine, paroxetine, propafenone, quinidine: May increase metoprolol level. Monitor vital signs.

Hydralazine: May increase levels and effects of both drugs. Monitor patient closely. May need to adjust dosage.

I.V. lidocaine: May reduce hepatic metabolism of lidocaine, increasing risk of toxicity. Give bolus doses of lidocaine at a slower rate, and monitor lidocaine level closely.

Terbutaline: May antagonize bronchodilatory effects of terbutaline. Monitor patient.

Verapamil: May increase effects of both drugs. Monitor cardiac function closely, and decrease dosages as needed.

Herb Ma huang: May decrease antihypertensive effects. Discourage use together.

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