Omeprazole

Omeprazole Uses

Omeprazole is used for Gastroesophageal Reflux Disease (GERD), Gastric Ulcer

How Omeprazole Works

Omeprazole works by decreasing the amount of acid made in the stomach.

Common side effects of Omeprazole

Headache, Diarrhea, Abdominal Pain, Nausea, Dizziness, Vomiting, Constipation, Rash, Cough

Interaction

Drug : alprazolam, astemizole, carbamazepine, cisapride, cyclosporine, diazepam, diltiazem, erythromycin, felodipine, lidocaine, lovastatin, midazolam, quinidine, simvastatin, terfenadine, triazolam, verapamil, voriconazole: Decreased clearance and increased blood levels of these drugs.

ampicillin, iron salts, itraconazole, ketoconazole, vitamin B12: Impaired absorption of these drugs.

atazanavir, nelfinavir: Decreased plasma atazanavir or nelfinavir level.

cilostazol: Increased blood cilostazol level.

clarithromycin: Increased blood levels of omeprazole and clarithromycinl.

digoxin: Increased digoxin bioavailability, possibly digitalis toxicity.

levobupivacaine: Increased risk of levobupivacaine toxicity.

methotrexate: Possibly delayed methotrexate elimination.

nifedipine: Decreased nifedipine clearance, increased risk of hypotension.

phenytoin: Decreased phenytoin clearance, increased risk of phenytoin toxicity.

saquinavir: Increased plasma saquinavir level.

sucralfate: Decreased omeprazole absorption.

tacrolimus: Possibly increased tacrolimus level.

warfarin: Possibly increased risk of abnormal bleeding.

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