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Pazopanib is used for Advanced Renal Cell Carcinoma, Soft-Tissue Sarcoma
How Pazopanib Works
Pazopanib works in RCC is through its antiangiogenic properties via inhibition of the intracellular tyrosine kinase of vascular endothelial growth factor receptor and platelet-derived growth factor receptor.
Common side effects of Pazopanib
Headache, Decreased Appetite, Weight Loss, Nausea, Pain, Breathing Difficulty, Vomiting, Abnormal Skin Pigmentation, Diarrhoea, Hair Discolouration, Increased Blood Pressure, Altered Taste, Musculoskeletal Pain, Fatigue, Tumor