Sertraline

Sertraline Uses

Sertraline is used for Depression, Obsessive-Compulsive Disorder, Panic Disorder, Posttraumatic Stress Disorder, Premenstrual Dysphoric Disorder, Social Anxiety Disorder

How Sertraline Works

Sertraline works by affecting the balance of chemicals in the brain. Specifically, it increases the level of a neurotransmitter called serotonin in the brain. Increased serotonin levels can help improve mood, reduce panic attacks, and treat OCD.

Common side effects of Sertraline

Fatigue, Headache, Dry Mouth, Nausea, Diarrhea, Loose Stools, Dyspepsia, Vomiting, Constipation, Abdominal Pain

Interaction

DrugAgents with antiplatelet properties (P2Y12 inhibitors, NSAIDs, SSRIs): May enhance antiplatelet effect.

Amphetamines, buspirone, dextromethorphan, dihydroergotamine, lithium salts, meperidine, other SSRIs or SSNRIs (duloxetine, venlafaxine), sumatriptan, TCAs, tramadol , trazodone, tryptophan: May increase the risk of serotonin syndrome.

Triptans: May cause serotonin syndrome (restlessness, hallucinations, loss of coordination, fast heartbeat, rapid changes in BP, increased body temperature, hyperreflexia, nausea, vomiting, and diarrhea) or neuroleptic malignant syndrome-like reactions.

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