Zonisamide

Zonisamide Uses

Zonisamide is used for Seizures

How Zonisamide Works

Zonisamide may stop seizures and suppress their foci by blocking sodium channels and reducing voltage-dependent, inward currents from calcium channels. This action stabilizes neuronal membranes and suppresses synchronized neuronal hyperactivity.

Common side effects of Zonisamide

Sleepiness, Decreased Appetite, Indigestion, Dizziness, Nausea, Vomiting, Agitation

Interaction

Drug : carbamazepine, phenobarbital, phenytoin, valproate: Possibly decreased blood zonisamide level.

CNS depressants: Additive CNS depressant effects.

Food : grapefruit juice: Possibly decreased metabolism of zonisamide.

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