Crizalk 250mg Capsule

Medically reviewed by Dr. Naresh Dang | Written By Sonu Kumar Rao

Last updated on: November 02, 2020 10:33 am

Crizalk 250mg Capsule

Uses of Crizalk 250mg Capsule

Crizalk 250mg Capsule is used for the treatment or prevention of the following disease(s):

Metastatic Non Small Cell Lung Cancer (NSCLC)

Side effects of Crizalk 250mg Capsule

The most common side effects of Crizalk 250mg Capsule are – Dizziness, Neuropathy, Headache, Insomnia, Fatigue, Fever, Chest Pain, Edema, Bradycardia, Visual Disorders, Nausea, Diarrhea, Vomiting, Constipation

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Crizalk 250mg Capsule

Do not use Crizalk 250mg Capsule if you are allergic to – Crizotinib

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Crizalk 250mg Capsule.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Crizalk 250mg Capsule works

Crizalk 250mg Capsule contains – Crizotinib

Crizotinib inhibits tyrosine kinase receptors, including ALK and other growth factors, decreasing tumor-cell proliferation.

Dosage of Crizalk 250mg Capsule

The dosage of Crizalk 250mg Capsule depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Crizalk 250mg Capsule

If you forget to take a dose of Crizalk 250mg Capsule, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings

Alcohol

Information will be added soon.

Pregnancy

Information will be added soon.

Breastfeeding

Information will be added soon.

Driving

Information will be added soon.

Kidney

Information will be added soon.

Liver

Information will be added soon.

Interaction

Drug :- CYP3A substrates (alfentanil, cyclosporine, dihydroergotamine, ergotamine, fentanyl, pimozide, quinidine, sirolimus, tacrolimus): May increase levels of these drugs. Avoid use together.

Moderate CYP3A inhibitors (aprepitant, diltiazem, erythromycin, fluconazole, verapamil): May increase crizotinib level. Use together cautiously.

P-glycoprotein substrates (daunorubicin, saquinavir, vinca alkaloids): May increase levels of these drugs. Avoid use together.

Strong CYP3A inducers (carbamazepine, phenobarbital, phenytoin, rifabutin, rifampin): May decrease crizotinib level. Avoid use together.

Strong CYP3A inhibitors (atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, troleandomycin, voriconazole): May increase crizotinib level. Avoid use together.

Herb :- St. John's wort: May decrease crizotinib level. Avoid use together.

Food :- Grapefruit, grapefruit juice: May increase crizotinib level. Avoid use together.

About Reviewer

Dr. Naresh Dang is an MD in Internal Medicine. He has special interest in the field of Diabetes, and has over two decades of professional experience in his chosen field of specialty. Dr. Dang is an expert in the managememnt of Diabetes, Hypertension and Lipids. He also provides consultation for Life Style Management.

About Author

Sonu Kumar is a registered pharmacist with Bihar State Pharmacy Council with over 6 months experience. He is a medicine content contributor at Zotezo.

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