Depin 5mg Capsule

Medically reviewed by Dr. Swaroop Choudhari | Written By Kunal V Kumar

Last updated on: November 02, 2020 3:17 am

Depin 5mg Capsule

Uses of Depin 5mg Capsule

Depin 5mg Capsule is used for the treatment or prevention of the following disease(s):

Hypertension, Chest Pain

Side effects of Depin 5mg Capsule

The most common side effects of Depin 5mg Capsule are – Dizziness, Light-Headedness, Fever, Abdominal Pain, Diarrhea, Dry Mouth, Dyspepsia, Flatulence, Weakness, Nervousness, Nervousness, Paresthesia, Somnolence, Flushing, Transient Hypotension, Dizziness

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Depin 5mg Capsule

Do not use Depin 5mg Capsule if you are allergic to – Nifedipine

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Depin 5mg Capsule.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Depin 5mg Capsule works

Depin 5mg Capsule contains – Nifedipine

Nifedipine is thought to inhibit calcium ion influx across cardiac and smooth muscle cells, decreasing contractility and oxygen demand. Drug may also dilate coronary arteries and arterioles.

Dosage of Depin 5mg Capsule

The dosage of Depin 5mg Capsule depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Depin 5mg Capsule

If you forget to take a dose of Depin 5mg Capsule, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings

Alcohol

Information will be added soon.

Pregnancy

Information will be added soon.

Breastfeeding

Information will be added soon.

Driving

Information will be added soon.

Kidney

Information will be added soon.

Liver

Information will be added soon.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

Calcigard 5mg Capsule  ( Torrent Pharmaceuticals Ltd. )

10.80  10 Capsules Strip Tablets Strip

Interaction

Drug :- ACE inhibitors (benazepril): May increase hypotensive effects. Monitor BP and adjust nifedipine dosage as needed.

Alpha blockers (doxazosin): May increase nifedipine plasma concentration. Monitor BP and adjust 1 nifedipine dosage as needed.

Antiretrovirals, cimetidine, verapamil: May decrease nifedipine metabolism. Monitor BP closely, adjust nifedipine dose as needed.

Azole antifungals, erythromycin, nefazodone, quinupristin-dalfopristin, valproic acid: May increase the effects of nifedipine. Monitor BP closely and decrease nifedipine dosage as needed.

Cyclosporine, tacrolimus: May increase serum levels of these drugs and increase risk of toxicity. Monitor serum levels and adjust dosage as needed.

Digoxin: May cause elevated digoxin level. Monitor digoxin level.

Diltiazem: May increase the effects of nifedipine. Monitor patient closely.

Diuretics, fentanyl: May increase hypotensive effects. Monitor BP.

Propranolol, other beta blockers: May cause hypotension and HF. Use together cautiously.

Quinidine: May decrease levels and effects of quinidine while increasing effects of nifedipine. Monitor HR and adjust nifedipine dose as needed.

Strong CYP3A4 inducers (carbamazepine, dexamethasone, phenytoin, rifabutin, rifampin): May decrease nifedipine level. Use together is contraindicated.

Warfarin: May increase PT. Monitor coagulation parameters and adjust warfarin dosage as needed.

Herb :- Ginkgo: May increase effects of drug. Discourage use together.

Ginseng: May increase drug levels with possible toxicity. Discourage use together.

Melatonin, St. John's wort: May interfere with antihypertensive effect. Discourage use together.

Food :- Grapefruit juice: May increase bioavailability of drug. Discourage use together.

About Reviewer

Dr. Swaroop Y Choudhari is an MBBS, MD in General Medicine. The doctor holds an experience of 8 years, and has extensive knowledge in his respective field of medicine.

About Author

Kunal is a registered pharmacist with RGUHS with over 11 months experience. He is a medicine content contributor at Zotezo.

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