Doloforce 20mg/ml Injection

  • Manufacturer : Mankind Pharma Ltd.
  • Composition : Piroxicam 20mg/ml
  • Generally Prescribed For : Osteoarthritis | Rheumatoid Arthritis
  • Estimated Price : 20.00 For 2ml Vial

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Uses of Doloforce 20mg/ml Injection

Doloforce 20mg/ml Injection is used for the treatment or prevention of the following disease(s):

Osteoarthritis, Rheumatoid Arthritis

Side effects of Doloforce 20mg/ml Injection

The most common side effects of Doloforce 20mg/ml Injection are - Depression, Dizziness, Dream Disturbances, Drowsiness, Fever, Headache, Insomnia, Ischemic Stroke, Malaise, Nervousness, Paresthesia, Somnolence, Syncope, Transient Ischemic Attack, Tremor, Vertigo

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Doloforce 20mg/ml Injection

Do not use Doloforce 20mg/ml Injection if you are allergic to - Piroxicam

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Doloforce 20mg/ml Injection.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Doloforce 20mg/ml Injection works

Doloforce 20mg/ml Injection contains - Piroxicam

Piroxicam blocks the activity of cyclooxygenase

the enzyme needed for prostaglandin synthesis. Prostaglandins

important mediators of the inflammatory response

cause local vasodilation with swelling and pain. By blocking cyclooxygenase activity and inhibiting prostaglandins

this NSAID reduces inflammatory symptoms and pain.

Dosage of Doloforce 20mg/ml Injection

The dosage of Doloforce 20mg/ml Injection depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Doloforce 20mg/ml Injection

If you forget to take a dose of Doloforce 20mg/ml Injection, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Overdose can have harmful effects on kidney or liver. Consult your doctor before taking this medicine to avoid an overdose.

Onset of Action Doloforce 20mg/ml Injection

It takes about 30 minutes to 1 hour to show the effect of the medicine.

Duration of Action Doloforce 20mg/ml Injection

Effect of medication lasts for an average of 48 to 72 hours.

Precautions & Warnings

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  • Alcohol Don't consume alcohol while taking this medicine; it may increase the risk of side effects. Adverse effects symptoms - Hypertension ; stomach bleeding (Presence of blood in cough or stool)

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  • Pregnancy Not recommended for pregnant women. Please consult your doctor before taking this medicine.

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  • Breastfeeding Not recommended for breastfeeding women. Please consult your doctor before taking this medicine.

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  • Driving Not safe during driving; you may feel dizzy or sleepy after taking this medicine.

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  • Kidney This medicine should be used with caution in patients with kidney disease. Consult your doctor before taking this medicine.

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  • Liver This medicine should be used with caution in patients with liver disease. Consult your doctor before taking this medicine.

Interaction

Drug :- acetaminophen: Possibly increased adverse renal effects with long-term use of both drugs.

antihypertensives: Possibly decreased or reversed effects of antihypertensives.

aspirin, other NSAIDs: Increased risk of bleeding and adverse GI effects, possibly increased blood piroxicam level.

cefamandole, cefoperazone, cefotetan: Increased risk of hypoprothrombinemia and bleeding.

colchicine: Increased risk of GI bleeding, hemorrhage, and ulcers.

corticosteroids, potassium supplements: Increased risk of adverse GI effects.

cyclosporine: Increased risk of nephrotoxicity from both drugs, increased blood cyclosporine level.

diuretics: Decreased antihypertensive, diuretic, and natriuretic effects of diuretics.

gold compounds, nephrotoxic drugs: Increased risk of adverse renal effects.

heparin, oral anticoagulants, thrombolytics: Increased anticoagulant effects, increased risk of hemorrhage.

insulin, oral antidiabetic drugs: Possibly increased hypoglycemic effect of these drugs.

lithium: Possibly increased blood lithium level and toxicity.

methotrexate: Decreased methotrexate clearance and increased risk of methotrexate toxicity.

platelet aggregation inhibitors: Increased risk of bleeding and GI ulceration or hemorrhage.

plicamycin, valproic acid: Increased risk of hypoprothrombinemia and GI bleeding,hemorrhage, and ulceration.

probenecid: Possibly increased blood level, effectiveness, and risk of toxicity of piroxicam.

Activity :- alcohol use: Increased risk of adverse GI effects.

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About Author

  • Dr. Swaroop Choudhari, MD
  • Dr. Swaroop Choudhari, MD Dr. Swaroop Y Choudhari is an MBBS, MD in General Medicine. The doctor holds an experience of 8 years, and has extensive knowledge in his respective f...
    ... ...

    Dr. Swaroop Choudhari, MD Dr. Swaroop Y Choudhari is an MBBS, MD in General Medicine. The doctor holds an experience of 8 years, and has extensive knowledge in his respective field of medicine.
    ... ...

About Author

  • Kunal V Kumar, B.Pharma
  • Kunal V Kumar, B.Pharma Kunal is a registered pharmacist with RGUHS with over 11 months experience. He is a medicine content contributor at Zotezo....

    Kunal V Kumar, B.Pharma Kunal is a registered pharmacist with RGUHS with over 11 months experience. He is a medicine content contributor at Zotezo.

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