Endoxan 50mg Tablet

Medically reviewed by Dr. Naresh Dang | Written By Sonu Kumar Rao

Last updated on: November 02, 2020 10:23 am

Endoxan 50mg Tablet

Uses of Endoxan 50mg Tablet

Endoxan 50mg Tablet is used for the treatment or prevention of the following disease(s):

Cancer (Breast, Blood, Head and Neck, Lung)

Side effects of Endoxan 50mg Tablet

The most common side effects of Endoxan 50mg Tablet are – Hair loss, Loss of appetite, Vomiting, Stomach pain, Nausea, Missed menstrual periods

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Endoxan 50mg Tablet

Do not use Endoxan 50mg Tablet if you are allergic to – Cyclophosphamide

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Endoxan 50mg Tablet.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Endoxan 50mg Tablet works

Endoxan 50mg Tablet contains – Cyclophosphamide

Cyclophosphamide cross-links strands of cellular DNA and interferes with RNA transcription, causing an imbalance of growth that leads to cell death. Not specific to cell cycle.

Dosage of Endoxan 50mg Tablet

The dosage of Endoxan 50mg Tablet depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Endoxan 50mg Tablet

If you forget to take a dose of Endoxan 50mg Tablet, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings


Information will be added soon.


Information will be added soon.


Information will be added soon.


Information will be added soon.


Information will be added soon.


Information will be added soon.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.


Drug :- Allopurinol, myelosuppressants: May increase myelosuppression. Monitor patient for toxicity.

Amiodarone: May increase risk of pulmonary toxicity. Monitor therapy.

Anticoagulants: May increase anticoagulant effect. Monitor patient for bleeding.

Aspirin, NSAIDs: May increase risk of bleeding. Avoid using together.

Azole antifungals (itraconazole): May increase exposure to cyclophosphamide and its metabolites. Closely monitor patient for cyclophosphamide adverse reactions.

Barbiturates: May enhance cyclophosphamide toxicity. Monitor patient closely.

Carbamazepine: May increase cyclophosphamide level. Monitor patient carefully and adjust cyclophosphamide dosage as needed.

Digoxin: May decrease digoxin level. Monitor level closely.

Live-virus vaccines: May increase vaccine-induced adverse reactions. Don't give together.

Pentostatin: May cause respiratory distress, hypotension, hypothermia, and death. Avoid use together if possible.

Phenytoin: May increase risk of cyclophosphamide toxicity. If coadministration can't be avoided, monitor patient carefully and consider reducing initial dose of cyclophosphamide.

Quinolones: May decrease the antimicrobial effects of quinolones. Monitor patient.

Succinylcholine: May prolong neuromuscular blockade. Avoid using together.

Thiazide diuretics: May prolong antineoplastic-induced leukopenia. Monitor patient closely.

TNF blockers: May increase the incidence of noncutaneous solid malignancies. Use together isn't recommended.

About Reviewer

Dr. Naresh Dang is an MD in Internal Medicine. He has special interest in the field of Diabetes, and has over two decades of professional experience in his chosen field of specialty. Dr. Dang is an expert in the managememnt of Diabetes, Hypertension and Lipids. He also provides consultation for Life Style Management.

About Author

Sonu Kumar is a registered pharmacist with Bihar State Pharmacy Council with over 6 months experience. He is a medicine content contributor at Zotezo.