Uses of Endoxan N 500mg Injection

Endoxan N 500mg Injection is used for the treatment or prevention of the following disease(s):

Cancer (Breast, Blood, Head and Neck, Lung)

Side effects of Endoxan N 500mg Injection

Precautions while taking Endoxan N 500mg Injection

Dosage of Endoxan N 500mg Injection

Overdose of Endoxan N 500mg Injection

Onset of Action of Endoxan N 500mg Injection

Duration of Action of Endoxan N 500mg Injection

Precautions & Warnings

Alcohol

Information will be added soon.

Pregnancy

Information will be added soon.

Breastfeeding

Information will be added soon.

Driving

Information will be added soon.

Kidney

Information will be added soon.

Liver

Information will be added soon.

Interactions

Drug :- Allopurinol, myelosuppressants: May increase myelosuppression. Monitor patient for toxicity.

Amiodarone: May increase risk of pulmonary toxicity. Monitor therapy.

Anticoagulants: May increase anticoagulant effect. Monitor patient for bleeding.

Aspirin, NSAIDs: May increase risk of bleeding. Avoid using together.

Azole antifungals (itraconazole): May increase exposure to cyclophosphamide and its metabolites. Closely monitor patient for cyclophosphamide adverse reactions.

Barbiturates: May enhance cyclophosphamide toxicity. Monitor patient closely.

Carbamazepine: May increase cyclophosphamide level. Monitor patient carefully and adjust cyclophosphamide dosage as needed.

Digoxin: May decrease digoxin level. Monitor level closely.

Live-virus vaccines: May increase vaccine-induced adverse reactions. Don't give together.

Pentostatin: May cause respiratory distress, hypotension, hypothermia, and death. Avoid use together if possible.

Phenytoin: May increase risk of cyclophosphamide toxicity. If coadministration can't be avoided, monitor patient carefully and consider reducing initial dose of cyclophosphamide.

Quinolones: May decrease the antimicrobial effects of quinolones. Monitor patient.

Succinylcholine: May prolong neuromuscular blockade. Avoid using together.

Thiazide diuretics: May prolong antineoplastic-induced leukopenia. Monitor patient closely.

TNF blockers: May increase the incidence of noncutaneous solid malignancies. Use together isn't recommended.

Kunal is a registered pharmacist with RGUHS with over 4 years experience. He is a medicine content contributor at Health-Shoppe.com.

Dr. Naresh Dang is an MD in Internal Medicine. He has special interest in the field of Diabetes, and has over two decades of professional experience in his chosen field of specialty. Dr. Dang is an expert in the management of Diabetes, Hypertension and Lipids. He also provides consultation for Life Style Management.