Epsolin 100mg Tablet

Medically reviewed by Dr. Swaroop Choudhari | Written By Kunal V Kumar

Last updated on: November 02, 2020 4:17 am

Epsolin 100mg Tablet

Uses of Epsolin 100mg Tablet

Epsolin 100mg Tablet is used for the treatment or prevention of the following disease(s):

Tonic-Clonic, Seizures

Side effects of Epsolin 100mg Tablet

The most common side effects of Epsolin 100mg Tablet are – Amblyopia, Conjunctivitis, Hearing Loss, Loss of Taste, Constipation,Diarrhea, Epigastric Pain, Hepatic Dysfunction, Hepatic Necrosis, Hepatitis, Nausea, Vomiting


These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Epsolin 100mg Tablet

Do not use Epsolin 100mg Tablet if you are allergic to – Phenytoin

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Epsolin 100mg Tablet.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Epsolin 100mg Tablet works

Epsolin 100mg Tablet contains – Phenytoin

Phenytoin works by decreasing abnormal electrical activity in the brain.

Dosage of Epsolin 100mg Tablet

The dosage of Epsolin 100mg Tablet depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Epsolin 100mg Tablet

If you forget to take a dose of Epsolin 100mg Tablet, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings

Alcohol

Information will be added soon.

Pregnancy

Information will be added soon.

Breastfeeding

Information will be added soon.

Driving

Information will be added soon.

Kidney

Information will be added soon.

Liver

Information will be added soon.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

Celetoin 100mg Tablet  ( Intas Pharmaceuticals Ltd. )

157.92  100 Tablets Bottle Tablets Strip

Fentinol 100mg Tablet  ( Knoll Pharmaceuticals Ltd. )

133.35  100 Tablets Bottle Tablets Strip

M Toin 100mg Tablet  ( Medo Pharma )

14.45  10 Tablets Strip Tablets Strip

Eptoin 100mg Tablet  ( Abbott India Ltd. )

195.83  120 Tablets Bottle Tablets Strip

Phenos 100mg Tablet  ( D D Pharmaceuticals )

13.60  10 Tablets Strip Tablets Strip

Interaction

Drug :- acetaminophen: Possibly hepatotoxicity, decreased acetaminophen effects.

activated charcoal, antacids, calcium salts, enteral feedings, sucralfate: Decreased absorption of oral phenytoin.

allopurinol, benzodiazepines, chloramphenicol, cimetidine, disulfiram, fluconazole, isoniazid, itraconazole, methylphenidate, metronidazole, miconazole, omeprazole, phenacemide, ranitidine, sulfonamides, trazodone, trimethoprim: Decreased metabolism and increased effects of phenytoin.

amiodarone, ticlopidine: Possibly increased blood phenytoin level.

antifungals azole: Increased blood phenytoin level, decreased blood antifungal level.

antineoplastics, nitrofurantoin, pyridoxine: Decreased phenytoin effects.

barbiturates: Variable effects on blood phenytoin level.

bupropion, clozapine, loxapine, MAO inhibitors, maprotiline, molindone, phenothiazines, pimozide, thioxanthenes, tricyclic antidepressants: Decreased seizure threshold, decreased anticonvulsant effects.

calcium channel blockers: Increased metabolism and decreased effects of these drugs, possibly increased blood phenytoin level.

carbamazepine: Decreased blood level and effects of carbamazepine, possibly phenytoin toxicity.

carbonic anhydrase inhibitors: Increased riskof osteopenia from phenytoin.

chlordiazepoxide, diazepam: Possibly increased blood phenytoin level, decreased effects of these drugs.

clonazepam: Possibly decreased blood level and effects of clonazepam, possibly phenytoin toxicity.

corticosteroids, cyclosporine, dicumarol, digoxin, disopyramide, doxycycline, estrogens, furosemide, lamotrigine, levodopa, methadone, metyrapone, mexiletine, oral contraceptives, quinidine, sirolimus, tacrolimus, theophylline: Increased metabolism and decreased effects of these drugs.

dopamine: Increased risk of severe hypotension and bradycardia with I.V. phenytoin.

fluoxetine: Increased blood phenytoin level and risk of phenytoin toxicity.

folic acid, leucovorin: Decreased blood phenytoin level, increased risk of seizures.

haloperidol: Decreased effects of haloperidol, decreased anticonvulsant effect of phenytoin.

halothane anesthetics: Increased risk of hepatotoxicity and phenytoin toxicity.

ifosfamide: Decreased phenytoin effects, possibly increased toxicity.

influenza virus vaccine: Possibly decreased phenytoin effects.

insulin, oral antidiabetic drugs: Possibly hyperglycemia, increased blood phenytoin level with tolbutamide.

levonorgestrel, mebendazole, streptozocin, sulfonylureas: Decreased effects of these drugs.

lidocaine, propranolol possibly other beta blockers: Increased cardiac depressant effects with I.V. phenytoin, possibly decreased blood level and increased adverse effects of phenytoin.

lithium: Increased risk of lithium toxicity, increased risk of neurologic symptoms with normal blood lithium level.

meperidine: Increased metabolism and decreased effects of meperidine, possibly meperidine toxicity.

methadone: Possibly increased metabolism of methadone and withdrawal symptoms.

neuromuscular blockers: Shorter duration of action and decreased effects of neuromuscular blockers.

oral anticoagulants: Decreased metabolism and increased effects of phenytoin, early increase and then decrease in anticoagulation.

paroxetine: Decreased bioavailability of both drugs.

phenylbutazone, salicylates: Increased phenytoin effects, possibly phenytoin toxicity primidone: Increased primidone effects, possibly primidone toxicity rifampin: Increased hepatic metabolism of phenytoin.

valproic acid: Possibly decreased phenytoin metabolism, resulting in increased phenytoin effects, possibly decreased blood valproic acid level vitamin D: Possibly decreased vitamin D effects, resulting in rickets or osteomalacia with long-term use of phenytoin.

Activity :- alcohol use: Additive CNS depression, increased phenytoin clearance.

About Reviewer

Dr. Swaroop Y Choudhari is an MBBS, MD in General Medicine. The doctor holds an experience of 8 years, and has extensive knowledge in his respective field of medicine.

About Author

Kunal is a registered pharmacist with RGUHS with over 11 months experience. He is a medicine content contributor at Zotezo.

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