Motivyst 300mg Tablet

Medically reviewed by Dr. Swaroop Choudhari | Written By Sonu Kumar Rao

Last updated on: November 02, 2020 10:16 am

Motivyst 300mg Tablet

Uses of Motivyst 300mg Tablet

Motivyst 300mg Tablet is used for the treatment or prevention of the following disease(s):


Side effects of Motivyst 300mg Tablet

The most common side effects of Motivyst 300mg Tablet are – Fatigue, Postural Dizziness, Thirst, Constipation, Nausea, Abdominal Pain, Dehydration, Urinary tract infections

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Motivyst 300mg Tablet

Do not use Motivyst 300mg Tablet if you are allergic to – Canagliflozin

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Motivyst 300mg Tablet.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Motivyst 300mg Tablet works

Motivyst 300mg Tablet contains – Canagliflozin

Canagliflozin inhibits sodium-glucose cotransporter 2, which reabsorbs glucose filtered by the kidneys, increasing amount of urinary glucose that is excreted.

Dosage of Motivyst 300mg Tablet

The dosage of Motivyst 300mg Tablet depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Motivyst 300mg Tablet

If you forget to take a dose of Motivyst 300mg Tablet, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings


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Drug :- ACE inhibitors (enalapril, lisinopril, moexipril, quinapril), ARBs (candesartan, losartan, olmesartan, valsartan), eplerenone, potassium-sparing diuretics (amiloride, spironolactone): May increase risk of hyperkalemia. Monitor potassium level closely.

Antihypertensives: May increase hypotension. Monitor patient closely.

Carbamazepine: May decrease canagliflozin serum concentration. Consider increasing canagliflozin dosage based on GFR.

Digoxin: May increase digoxin level. Monitor digoxin level periodically.

Insulin and insulin secretagogues (glipizide, repaglinide): May increase risk of hypoglycemia.

Consider lower dosage of insulin or insulin secretagogue.

Lomitapide: May increase lomitapide level. Limit maximum adult dosage of lomitapide to 30 mg daily.

Loop diuretics: May cause hypotension and intravascular volume depletion. Consider alternative therapy.

Salicylates: May increase hypoglycemic effects. Monitor patient closely.

SSRIs (citalopram, fluoxetine, sertraline): May increase canagliflozin level. Monitor patient closely.

Canagliflozin dosage may need adjustment if SSRI is discontinued.

UGT inducers (phenobarbital, phenytoin, rifampin, ritonavir): May decrease canagliflozin level.

Adjust canagliflozin dosage based on estimated GFR.

Herb :- St. John's wort: May decrease canagliflozin serum concentration. Consider increasing canagliflozin dosage based on GFR.

About Reviewer

Dr. Swaroop Y Choudhari is an MBBS, MD in General Medicine. The doctor holds an experience of 8 years, and has extensive knowledge in his respective field of medicine.

About Author

Sonu Kumar is a registered pharmacist with Bihar State Pharmacy Council with over 6 months experience. He is a medicine content contributor at Zotezo.