Uses of Paxonil Plus 12.5mg/0.5mg Tablet

Paxonil Plus 12.5mg/0.5mg Tablet is used for the treatment or prevention of the following disease(s):

Depression, Obsessive Compulsive Disorder, Anxiety Disorder, Premenstrual Dysphoric Disorder

Side effects of Paxonil Plus 12.5mg/0.5mg Tablet

Precautions while taking Paxonil Plus 12.5mg/0.5mg Tablet

Dosage of Paxonil Plus 12.5mg/0.5mg Tablet

Overdose of Paxonil Plus 12.5mg/0.5mg Tablet

Onset of Action of Paxonil Plus 12.5mg/0.5mg Tablet

Duration of Action of Paxonil Plus 12.5mg/0.5mg Tablet

Precautions & Warnings

Alcohol

Information will be added soon.

Pregnancy

Information will be added soon.

Breastfeeding

Information will be added soon.

Driving

Information will be added soon.

Kidney

Information will be added soon.

Liver

Information will be added soon.

All substitutes for Paxonil Plus 12.5mg/0.5mg Tablet

For information purpose only. Refer to a healthcare professionals before consuming any medicines and/or drugs.

Interactions

Drug :- antacids: Hastened release of C.R. paroxetine aspirin, NSAIDs, warfarin: Increased anticoagulant activity and risk of bleeding.

astemizole: Increased risk of arrhythmias.

atomoxetine, risperidone, other drugs metabolized by CYP2D6, such as amitriptyline, desipramine, fluoxetine, imipramine, phenothiazines, tamoxifen, type IC antiarrhythmics: Increased plasma levels of these drugs.

barbiturates, primidone: Decreased blood paroxetine level.

cimetidine: Possibly increased blood paroxetine level.

cisapride, isoniazid, MAO inhibitors, procarbazine: Possibly serotonin syndrome.

codeine, haloperidol, metoprolol, perphenazine, propranolol, risperidone, thioridazine: Decreased metabolism and increased effects of these drugs.

cyproheptadine: Decreased paroxetine effects.

dextromethorphan: Decreased dextromethorphan metabolism and increased risk of toxicity.

digoxin: Possibly decreased digoxin effects.

encainide, flecainide, propafenone, quinidine: Potentiated toxicity of these drugs.

fosamprenavir, ritonavir: Decreased plasma paroxetine level.

lithium: Possibly increased blood paroxetine level, increased risk of serotonin syndrome.

methadone: Decreased methadone metabolism, increased risk of adverse effects.

phenytoin: Possibly phenytoin toxicity.

pimozide: Increased risk of prolonged QT interval.

procyclidine: Increased blood procyclidine level and anticholinergic effects.

serotonergic drugs such as linezolid, St. John's wort, tramadol, triptans, and tryptophan: Increased risk of serotonin syndrome.

tamoxifen: Decreased tamoxifen effectiveness.

theophylline: Possibly increased blood theophylline level and risk of toxicity.

thioridazine: Increased thioridazine level, possibly leading to prolonged QT interval and life-threatening ventricular arrhythmias.

tramadol: Increased risk of serotonin syndrome and seizures.

tricyclic antidepressants: Increased metabolism and blood antidepressant levels, increased risk of toxicity, including seizures.

Kunal is a registered pharmacist with RGUHS with over 4 years experience. He is a medicine content contributor at Health-Shoppe.com.

Dr. Naresh Dang is an MD in Internal Medicine. He has special interest in the field of Diabetes, and has over two decades of professional experience in his chosen field of specialty. Dr. Dang is an expert in the management of Diabetes, Hypertension and Lipids. He also provides consultation for Life Style Management.