Pemgem 500mg Injection

Medically reviewed by Dr. Naresh Dang | Written By Sonu Kumar Rao

Last updated on: November 02, 2020 10:54 am

Pemgem 500mg Injection

Uses of Pemgem 500mg Injection

Pemgem 500mg Injection is used for the treatment or prevention of the following disease(s):

Non-Small Cell Lung Cancer

Side effects of Pemgem 500mg Injection

The most common side effects of Pemgem 500mg Injection are – Depression, Emboli, Thrombosis, Fatigue, Esophagitis, Painful, Difficult Swallowing, Taste Disturbance, Fever, Neuropathy, Cardiac Ischemia, Anorexia, Constipation, Diarrhea, Nausea, Chest Pain, Edema, Pharyngitis, Conjunctivitis, Stomatitis, Vomiting

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Pemgem 500mg Injection

Do not use Pemgem 500mg Injection if you are allergic to – Pemetrexed

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Pemgem 500mg Injection.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Pemgem 500mg Injection works

Pemgem 500mg Injection contains – Pemetrexed

Pemetrexed disturbs cell replication by inhibiting several folate-dependent enzymes involved in nucleotide synthesis. When given with other antineoplastics, drug inhibits growth of mesothelioma cell lines.

Dosage of Pemgem 500mg Injection

The dosage of Pemgem 500mg Injection depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Pemgem 500mg Injection

If you forget to take a dose of Pemgem 500mg Injection, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings


Information will be added soon.


Information will be added soon.


Information will be added soon.


Information will be added soon.


Information will be added soon.


Information will be added soon.


Drug :- Nephrotoxic drugs, probenecid: May delay pemetrexed clearance. Monitor patient.

NSAIDs: May decrease pemetrexed clearance in patients with mild to moderate renal insufficiency.

For NSAIDs with short half-lives, avoid use for 2 days before, during, and 2 days after pemetrexed therapy. For NSAIDs with long half-lives, avoid use for 5 days before, during, and 2 days after pemetrexed therapy.

About Reviewer

Dr. Naresh Dang is an MD in Internal Medicine. He has special interest in the field of Diabetes, and has over two decades of professional experience in his chosen field of specialty. Dr. Dang is an expert in the managememnt of Diabetes, Hypertension and Lipids. He also provides consultation for Life Style Management.

About Author

Sonu Kumar is a registered pharmacist with Bihar State Pharmacy Council with over 6 months experience. He is a medicine content contributor at Zotezo.