Phenykem 300mg Tablet
- Manufacturer : Alkem Laboratories Ltd.
- Composition : Phenytoin 300mg
- Generally Prescribed For : Tonic-Clonic, Seizures
- Estimated Price : ₹48.08 For 10 Tablets Strip
BUY FROM THESE SELLERS
Uses of Phenykem 300mg TabletPhenykem 300mg Tablet is used for the treatment or prevention of the following disease(s):
Side effects of Phenykem 300mg TabletThe most common side effects of Phenykem 300mg Tablet are - Amblyopia, Conjunctivitis, Hearing Loss, Loss of Taste, Constipation,Diarrhea, Epigastric Pain, Hepatic Dysfunction, Hepatic Necrosis, Hepatitis, Nausea, Vomiting
These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.
Precautions while using Phenykem 300mg TabletDo not use Phenykem 300mg Tablet if you are allergic to - Phenytoin
If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Phenykem 300mg Tablet.
If you are allergic to any medicine or food, consult your doctor before using this medicine.
Use this medicine under the supervision of your doctor.
To avoid an adverse reaction, consult your doctor if you are already taking other medicines.
How Phenykem 300mg Tablet worksPhenykem 300mg Tablet contains - Phenytoin
Phenytoin works by decreasing abnormal electrical activity in the brain.
Dosage of Phenykem 300mg TabletThe dosage of Phenykem 300mg Tablet depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.
Please use this medicine as prescribed by your doctor.
Overdose of Phenykem 300mg TabletIf you forget to take a dose of Phenykem 300mg Tablet, do not take two doses at the same time, there is a risk of overdose.
If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.
Precautions & Warnings
For informational purposes only. Consult a doctor before taking any medicines.
Eptoin 300mg Tablet ER
Abbott India Ltd.
30 Tablets Strip Tablets Strip
InteractionDrug :- acetaminophen: Possibly hepatotoxicity, decreased acetaminophen effects.
activated charcoal, antacids, calcium salts, enteral feedings, sucralfate: Decreased absorption of oral phenytoin.
allopurinol, benzodiazepines, chloramphenicol, cimetidine, disulfiram, fluconazole, isoniazid, itraconazole, methylphenidate, metronidazole, miconazole, omeprazole, phenacemide, ranitidine, sulfonamides, trazodone, trimethoprim: Decreased metabolism and increased effects of phenytoin.
amiodarone, ticlopidine: Possibly increased blood phenytoin level.
antifungals azole: Increased blood phenytoin level, decreased blood antifungal level.
antineoplastics, nitrofurantoin, pyridoxine: Decreased phenytoin effects.
barbiturates: Variable effects on blood phenytoin level.
bupropion, clozapine, loxapine, MAO inhibitors, maprotiline, molindone, phenothiazines, pimozide, thioxanthenes, tricyclic antidepressants: Decreased seizure threshold, decreased anticonvulsant effects.
calcium channel blockers: Increased metabolism and decreased effects of these drugs, possibly increased blood phenytoin level.
carbamazepine: Decreased blood level and effects of carbamazepine, possibly phenytoin toxicity.
carbonic anhydrase inhibitors: Increased riskof osteopenia from phenytoin.
chlordiazepoxide, diazepam: Possibly increased blood phenytoin level, decreased effects of these drugs.
clonazepam: Possibly decreased blood level and effects of clonazepam, possibly phenytoin toxicity.
corticosteroids, cyclosporine, dicumarol, digoxin, disopyramide, doxycycline, estrogens, furosemide, lamotrigine, levodopa, methadone, metyrapone, mexiletine, oral contraceptives, quinidine, sirolimus, tacrolimus, theophylline: Increased metabolism and decreased effects of these drugs.
dopamine: Increased risk of severe hypotension and bradycardia with I.V. phenytoin.
fluoxetine: Increased blood phenytoin level and risk of phenytoin toxicity.
folic acid, leucovorin: Decreased blood phenytoin level, increased risk of seizures.
haloperidol: Decreased effects of haloperidol, decreased anticonvulsant effect of phenytoin.
halothane anesthetics: Increased risk of hepatotoxicity and phenytoin toxicity.
ifosfamide: Decreased phenytoin effects, possibly increased toxicity.
influenza virus vaccine: Possibly decreased phenytoin effects.
insulin, oral antidiabetic drugs: Possibly hyperglycemia, increased blood phenytoin level with tolbutamide.
levonorgestrel, mebendazole, streptozocin, sulfonylureas: Decreased effects of these drugs.
lidocaine, propranolol possibly other beta blockers: Increased cardiac depressant effects with I.V. phenytoin, possibly decreased blood level and increased adverse effects of phenytoin.
lithium: Increased risk of lithium toxicity, increased risk of neurologic symptoms with normal blood lithium level.
meperidine: Increased metabolism and decreased effects of meperidine, possibly meperidine toxicity.
methadone: Possibly increased metabolism of methadone and withdrawal symptoms.
neuromuscular blockers: Shorter duration of action and decreased effects of neuromuscular blockers.
oral anticoagulants: Decreased metabolism and increased effects of phenytoin, early increase and then decrease in anticoagulation.
paroxetine: Decreased bioavailability of both drugs.
phenylbutazone, salicylates: Increased phenytoin effects, possibly phenytoin toxicity primidone: Increased primidone effects, possibly primidone toxicity rifampin: Increased hepatic metabolism of phenytoin.
valproic acid: Possibly decreased phenytoin metabolism, resulting in increased phenytoin effects, possibly decreased blood valproic acid level vitamin D: Possibly decreased vitamin D effects, resulting in rickets or osteomalacia with long-term use of phenytoin.
Activity :- alcohol use: Additive CNS depression, increased phenytoin clearance.