R-Cin 450mg Capsule

Medically reviewed by Dr. Swaroop Choudhari | Written By Kunal V Kumar

Last updated on: November 02, 2020 3:05 am

R-Cin 450mg Capsule

Uses of R-Cin 450mg Capsule

R-Cin 450mg Capsule is used for the treatment or prevention of the following disease(s):

Tuberculosis (TB)

Side effects of R-Cin 450mg Capsule

The most common side effects of R-Cin 450mg Capsule are – Abdominal Pain, Headache, Muscle Aches, Fever, Chills, Yellowing Eyes

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using R-Cin 450mg Capsule

Do not use R-Cin 450mg Capsule if you are allergic to – Rifampicin

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using R-Cin 450mg Capsule.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How R-Cin 450mg Capsule works

R-Cin 450mg Capsule contains – Rifampicin

Rifampicin inhibits bacterial and mycobacterial RNA synthesis by binding to DNA-dependent RNA polymerase, thereby blocking RNA transcription. Exhibits dose-dependent bactericidal or bacteriostatic action.

Dosage of R-Cin 450mg Capsule

The dosage of R-Cin 450mg Capsule depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of R-Cin 450mg Capsule

If you forget to take a dose of R-Cin 450mg Capsule, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings


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Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.


Drug :- aminophylline, oxtriphylline, theophylline: Increased metabolism and clearance of these theophylline preparations.

anesthetics hydrocarbon inhalation, except isoflurane, hepatotoxic drugs, isoniazid: Increased risk of hepatotoxicity.

beta blockers, chloramphenicol, clofibrate, corticosteroids, cyclosporine, dapsone, digitalis glycosides, disopyramide, hexobarbital, itraconazole, ketoconazole, mexiletine, oral anticoagulants, oral antidiabetic drugs, phenytoin, propafenone, quinidine, tocainide, verapamil oral: Increased metabolism, resulting in lower blood levels of these drug.

bone marrow depressants: Increased leukopenic or thrombocytopenic effects.

clofazimine: Reduced absorption of rifampin, delaying its peak concentration and increasing its half-life.

diazepam: Enhanced diazepam elimination, resulting in decreased drug effectiveness.

estramustine, estrogens, oral contraceptives: Decreased estrogenic effects.

methadone: Possibly impaired absorption of methadone, leading to withdrawal symptoms.

probenecid: Increased blood level or prolonged duration of rifampin, increasing risk of toxicity.

nonnucleoside reverse transcriptase inhibitors, protease inhibitors indinavir, nelfinavir, ritonavir, saquinavir: Accelerated metabolism of these drugs by patients with HIV, resulting in subtherapeutic levels,delayed metabolism of rifampin, increasing risk of toxicity.

trimethoprim: Increased elimination and shortened elimination half-life of trimethoprim.

vitamin D: Increased metabolism and decreased efficacy of vitamin D, leading to decreased serum calcium and phosphate levels and increased parathyroid hormone levels.

Activity :- alcohol use: Increased risk of hepatotoxicity.

About Reviewer

Dr. Swaroop Y Choudhari is an MBBS, MD in General Medicine. The doctor holds an experience of 8 years, and has extensive knowledge in his respective field of medicine.

About Author

Kunal is a registered pharmacist with RGUHS with over 11 months experience. He is a medicine content contributor at Zotezo.