- Manufacturer : Lupin Ltd.
- Composition : Rifampicin 100mg, Isoniazid 50mg
- Generally Prescribed For : Tuberculosis (TB)
- Estimated Price : ₹46.25 For 10 Tablets Strip
table of contents
Table of Contents
Table of Contents
Uses of R-Cinex 100mg/50mg Tablet
R-Cinex 100mg/50mg Tablet is used for the treatment or prevention of the following disease(s):
Tuberculosis (TB)
Side effects of R-Cinex 100mg/50mg Tablet
The most common side effects of R-Cinex 100mg/50mg Tablet are – Abdominal Pain, Headache, Muscle Aches, Fever, Chills, Yellowing Eyes
These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.
Precautions while using R-Cinex 100mg/50mg Tablet
Do not use R-Cinex 100mg/50mg Tablet if you are allergic to – Rifampicin, Isoniazid
If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using R-Cinex 100mg/50mg Tablet.
If you are allergic to any medicine or food, consult your doctor before using this medicine.
Use this medicine under the supervision of your doctor.
To avoid an adverse reaction, consult your doctor if you are already taking other medicines.
How R-Cinex 100mg/50mg Tablet works
R-Cinex 100mg/50mg Tablet contains – Rifampicin, Isoniazid
Rifampicin inhibits bacterial and mycobacterial RNA synthesis by binding to DNA-dependent RNA polymerase, thereby blocking RNA transcription. Exhibits dose-dependent bactericidal or bacteriostatic action.
Isoniazid works by killing the bacteria that causes Tuberculosis.
Dosage of R-Cinex 100mg/50mg Tablet
The dosage of R-Cinex 100mg/50mg Tablet depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.
Please use this medicine as prescribed by your doctor.
Overdose of R-Cinex 100mg/50mg Tablet
If you forget to take a dose of R-Cinex 100mg/50mg Tablet, do not take two doses at the same time, there is a risk of overdose.
If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.
Precautions & Warnings
Alcohol
Information will be added soon.
Pregnancy
Information will be added soon.
Breastfeeding
Information will be added soon.
Driving
Information will be added soon.
Kidney
Information will be added soon.
Liver
Information will be added soon.
Interaction
Drug :- aminophylline, oxtriphylline, theophylline: Increased metabolism and clearance of these theophylline preparations.
anesthetics hydrocarbon inhalation, except isoflurane, hepatotoxic drugs, isoniazid: Increased risk of hepatotoxicity.
beta blockers, chloramphenicol, clofibrate, corticosteroids, cyclosporine, dapsone, digitalis glycosides, disopyramide, hexobarbital, itraconazole, ketoconazole, mexiletine, oral anticoagulants, oral antidiabetic drugs, phenytoin, propafenone, quinidine, tocainide, verapamil oral: Increased metabolism, resulting in lower blood levels of these drug.
bone marrow depressants: Increased leukopenic or thrombocytopenic effects.
clofazimine: Reduced absorption of rifampin, delaying its peak concentration and increasing its half-life.
diazepam: Enhanced diazepam elimination, resulting in decreased drug effectiveness.
estramustine, estrogens, oral contraceptives: Decreased estrogenic effects.
methadone: Possibly impaired absorption of methadone, leading to withdrawal symptoms.
probenecid: Increased blood level or prolonged duration of rifampin, increasing risk of toxicity.
nonnucleoside reverse transcriptase inhibitors, protease inhibitors indinavir, nelfinavir, ritonavir, saquinavir: Accelerated metabolism of these drugs by patients with HIV, resulting in subtherapeutic levels,delayed metabolism of rifampin, increasing risk of toxicity.
trimethoprim: Increased elimination and shortened elimination half-life of trimethoprim.
vitamin D: Increased metabolism and decreased efficacy of vitamin D, leading to decreased serum calcium and phosphate levels and increased parathyroid hormone levels.
Activity :- alcohol use: Increased risk of hepatotoxicity.
