- Manufacturer : Pfizer Ltd.
- Composition : Sirolimus 1mg
- Generally Prescribed For : To Prevent Rejection of Kidney Transplantation
- Estimated Price : ₹3,709.67 For 10 Tablets Strip
table of contents
Table of Contents
Table of Contents
Uses of Rapamune 1mg Tablet
Rapamune 1mg Tablet is used for the treatment or prevention of the following disease(s):
To Prevent Rejection of Kidney Transplantation
Side effects of Rapamune 1mg Tablet
The most common side effects of Rapamune 1mg Tablet are – Fever, Headache, Insomnia, Tremor, Abdominal Pain, Constipation, Diarrhea, Elevated Liver Enzymes, Hepatotoxicity, Nausea, Vomiting, Anemia, Lymphoma, Neutropenia, Pancytopenia, Thrombocytopenia
These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.
Precautions while using Rapamune 1mg Tablet
Do not use Rapamune 1mg Tablet if you are allergic to – Sirolimus
If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Rapamune 1mg Tablet.
If you are allergic to any medicine or food, consult your doctor before using this medicine.
Use this medicine under the supervision of your doctor.
To avoid an adverse reaction, consult your doctor if you are already taking other medicines.
How Rapamune 1mg Tablet works
Rapamune 1mg Tablet contains – Sirolimus
Sirolimus inhibits activation and proliferation of T lymphocytes and antibody production. Sirolimus also inhibits cell cycle progression from the G1 to the S phase, possibly by inhibiting a key regulatory kinase believed to suppress cytokine-driven T-cell proliferation.
Dosage of Rapamune 1mg Tablet
The dosage of Rapamune 1mg Tablet depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.
Please use this medicine as prescribed by your doctor.
Overdose of Rapamune 1mg Tablet
If you forget to take a dose of Rapamune 1mg Tablet, do not take two doses at the same time, there is a risk of overdose.
If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.
Precautions & Warnings
Alcohol
Information will be added soon.
Pregnancy
Information will be added soon.
Breastfeeding
Information will be added soon.
Driving
Information will be added soon.
Kidney
Information will be added soon.
Liver
Information will be added soon.
Interaction
Drug :- aminoglycosides, amphotericin B, cyclosporine: Possibly impaired renal function.
bromocriptine, cimetidine, cisapride, clarithromycin, clotrimazole, cyclosporine, danazol, diltiazem, erythromycin, fluconazole, indinavir, itraconazole, ketoconazole, metoclopramide, nicardipine, ritonavir, troleandomycin, verapamil: Possibly increased blood sirolimus level and toxicity.
calcineurin inhibitors, corticosteroids: Increased risk of deteriorating renal function, serum lipid abnormalities, and UTI.
carbamazepine, phenobarbital, phenytoin, rifabutin, rifapentine, St. John's wort: Possibly decreased blood sirolimus level.
HMG-CoA reductase inhibitors: Increased risk of rhabdomyolysis when administered.
concurrently with sirolimus and cyclosporine rifampin: Significantly increased sirolimus clearance.
vaccines killed virus: Possibly decreased immune response to vaccines.
vaccines live virus: Increased risk of contracting disease from live virus.
Food :- grapefruit juice: Possibly decreased metabolism of sirolimus.
high-fat diet: Reduced rate of sirolimus absorption.
