Unicontin-E 600mg Tablet CR

Medically reviewed by Dr. Swaroop Choudhari | Written By Kunal V Kumar

Last updated on: November 02, 2020 3:44 am

Unicontin-E 600mg Tablet CR

Uses of Unicontin-E 600mg Tablet CR

Unicontin-E 600mg Tablet CR is used for the treatment or prevention of the following disease(s):

Lung Diseases (Asthma, Bronchitis, Emphysema), Shortness of Breath

Side effects of Unicontin-E 600mg Tablet CR

The most common side effects of Unicontin-E 600mg Tablet CR are – Confusion, Headache, Insomnia, Nervousness, Hypotension, Restlessness, Abdominal Pain, Diarrhea, Heartburn, Nausea, Vomiting

These side effects can usually occur in patients. However, these are only indicative and not all patients will experience them.

Precautions while using Unicontin-E 600mg Tablet CR

Do not use Unicontin-E 600mg Tablet CR if you are allergic to – Theophylline

If you have heart disease, liver or kidney disease, drug or alcohol addiction, consult your doctor before using Unicontin-E 600mg Tablet CR.

If you are allergic to any medicine or food, consult your doctor before using this medicine.

Use this medicine under the supervision of your doctor.

To avoid an adverse reaction, consult your doctor if you are already taking other medicines.

How Unicontin-E 600mg Tablet CR works

Unicontin-E 600mg Tablet CR contains – Theophylline

Theophylline inhibits phosphodiesterase enzymes, causing bronchodilation. Normally, these enzymes inactivate cAMP and cGMP, which are responsible for bronchial smoothmuscle relaxation. Theophylline also may cause calcium translocation, antagonize prostaglandins and adenosine receptors, stimulate catecholamines, and inhibit cGMP metabolism.

Dosage of Unicontin-E 600mg Tablet CR

The dosage of Unicontin-E 600mg Tablet CR depends on many factors such as the patient age, health, medical condition or history of the patient and many other conditions.

Please use this medicine as prescribed by your doctor.

Overdose of Unicontin-E 600mg Tablet CR

If you forget to take a dose of Unicontin-E 600mg Tablet CR, do not take two doses at the same time, there is a risk of overdose.

If you notice any unusual reaction in your body after taking this medicine, contact your doctor immediately or call your local medical emergency number.

Precautions & Warnings


Information will be added soon.


Information will be added soon.


Information will be added soon.


Information will be added soon.


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Information will be added soon.


Drug :- adenosine: Decreased adenosine effectiveness allopurinol, cimetidine, ciprofloxacin, clarithromycin, disulfiram, enoxacin, erythromycin, fluvoxamine, interferon alpha human recombinant, methotrexate, mexiletine, pentoxifylline, propafenone, propranolol, tacrine, thiabendazole, ticlopidine, troleandomycin, verapamil: Increased blood theophylline level and risk of toxicity.

aminoglutethimide, carbamazepine, isoproterenol I.V., moricizine, oral contraceptives containing estrogen, phenobarbital, phenytoin, rifampin: Decreased blood theophylline level and possibly drug effectiveness.

benzodiazepines: Possibly reversal of benzodiazepine sedation.

beta blockers: Possibly decreased bronchodilator effect of theophylline.

ephedrine: Increased adverse effects, including insomnia, nausea, and nervousness.

halothane anesthetics: Increased risk of ventricular arrhythmias.

ketamine: Lowered seizure threshold.

lithium: Decreased lithium effectiveness.

neuromuscular blockers: Possibly antagonized neuromuscular blockade.

sucralfate: Decreased absorption of oral theophylline.

Food :- high-carbohydrate, low-protein diet: Possibly decreased theophylline elimination.

low-carbohydrate, high-protein diet, daily intake of charbroiled beef: Possibly increased theophylline elimination.

Activity :- alcohol use: Increased blood theophylline level and risk of toxicity.

smoking: Increased drug clearance, decreased drug effectiveness.

About Reviewer

Dr. Swaroop Y Choudhari is an MBBS, MD in General Medicine. The doctor holds an experience of 8 years, and has extensive knowledge in his respective field of medicine.

About Author

Kunal is a registered pharmacist with RGUHS with over 11 months experience. He is a medicine content contributor at Zotezo.