Introduction

Silybum Marianum is the scientific name of milk thistle, a herbal plant. Silybin or silibinin is an active compound in milk thistle and is derived from the seeds of this plant. Doctors and Ayurveda practitioners have been using this herb for a long time, managing many disorders, especially liver issues. 

The Best Milk Thistle Supplements in USA are the ones that will help the body overcome liver stress due to multiple factors like chemicals, alcohol, and drugs. The liver is the largest organ of the body, working continuously to protect us from chemicals and toxic compounds. Therefore, its health is our priority. Milk thistle helps in maintaining the health of this organ.With multiple options of milk thistle supplements present in the market, it might be an overwhelming task to choose one. Don’t worry. We have got you covered.

This article features a list of top 7 Best Milk Thistle Supplements in USA. Buy the best supplement because a healthy mind resides in a healthy body. So keep reading to find out more about the best milk thistle supplements.

Milk Thistle Supplements in USA

Our pick of the 7 best milk thistle supplements of 2024 in USA

Let's take a deep dive into these 7 best Milk Thistle Supplements in USA

Best Overall Milk Thistle Supplements in USA

Zazzee Naturals

A+

Zotezo review

The Zazzee USDA Organic Milk Thistle 30:1 Extract offers a high-strength dosage of 7500 mg per capsule with 80% Silymarin Flavonoids, making it a potent and vegetarian-friendly supplement. However, some users may experience stomach upset or slight gastrointestinal discomfort.

Product details

  • 7500 mg strength per capsule

  • 120 vegan capsules per bottle

  • 80% Silymarin Flavonoids

  • Standardized and Concentrated 30X Extract

  • 100% Vegetarian

  • Non-GMO

Benefits of Zazzee Organic Milk Thistle Extr...

  • High strength - 7500 mg per capsule

  • 80% Silymarin Flavonoids

  • 100% Vegetarian

  • Non-GMO

Drawbacks

  • May cause stomach upset in some individuals

  • Slight gastrointestinal discomfort possible

A+

Zotezo review

The Bronson Milk Thistle Silymarin Marianum & Dandelion Root Liver Health Support supplement offers high potency antioxidant and detox support at a reasonable price with fast shipping. While highly recommended by many customers, it’s worth noting that effectiveness may vary among individuals and some users may experience mild side effects.

Product details

  • Liver Health Support

  • High Potency

  • Antioxidant Support

  • Detox Support

Benefits of Bronson Liver Health Support Cap...

  • Reasonable price

  • Fast shipping

  • Highly recommended by customers

Weaknesses

  • May not work the same for everyone

  • Some users may experience mild side effects

A+

Zotezo review

The Nutricost Milk Thistle 250mg (1000mg Equivalent) offers a high-quality, non-GMO, and gluten-free option with a 6-month supply. While it boasts a high absorption rate and transparency in sourcing, some users may consider the price relatively high and the concentration per capsule lower than desired for certain individuals.

Product details

  • 6 Month Supply

  • 250mg per Capsule (1,000mg Equivalent)

  • Premium Grade, 4:1 Extract

  • Non-GMO & Gluten Free

Benefits of Nutricost Milk Thistle Capsules,...

  • High absorption rate

  • Pure product with transparency of source and processing

  • Non-GMO and Gluten Free

Disadvantages

  • Some users may find the price to be on the higher side

  • The product may not be suitable for individuals looking for a higher concentration of milk thistle extract per capsule

A

Zotezo review

Puritan’s Pride Milk Thistle 4:1 Extract 1000 Mg Softgels offer effective liver support with antioxidant properties at a competitive price on Amazon. However, some users may find the larger softgel size and limited quantity per package to be drawbacks.

Product details

  • Milk Thistle 4:1 Extract

  • 1000 Mg Strength

  • Silymarin Softgels

  • Liver Support

  • 180 Count

  • Antioxidant Properties

Benefits of Puritan’s Pride Milk Thist...

  • Effective liver support

  • Easy to swallow softgels

  • Competitive pricing on Amazon

Negatives

  • Some users may find the softgel size to be a bit larger than expected

  • Limited quantity in each package (180 count)

A

Zotezo review

Overall, the Nature’s Bounty Milk Thistle supplement is a good value for supporting liver health with its 1000 mg concentration and easy-to-swallow rapid release softgels. However, it may not be effective for everyone and some users might dislike the taste.

Product details

  • Milk Thistle herbal health supplement

  • Supports liver health

  • 1000 mg concentration

  • Rapid release softgels

  • 50 count packaging

Benefits of Nature’s Bounty Milk Thist...

  • Supports liver health

  • Easy to swallow

  • Good value for the money

Cons

  • May not work for everyone

  • Some users may find the taste unpleasant

A

Zotezo review

The Carlyle Milk Thistle 2000mg capsules with Dandelion and Yellow Dock offer a potent herbal blend for liver support in a convenient non-GMO, gluten-free formula. While some users may find the taste strong and effects may take time to notice, this product provides a comprehensive liver-supporting solution.

Product details

  • Milk Thistle traditional herb

  • Herbal blend with Dandelion and Yellow Dock

  • Equivalent of 2000mg Milk Thistle

  • Non-GMO and Gluten-free

  • 180 capsules in one bottle

Benefits of Carlyle Milk Thistle 2000mg Caps...

  • Liver support

  • Contains Dandelion & Yellow Dock

  • Non-GMO & Gluten-free

Drawbacks

  • May take time to notice effects

  • Strong taste for some individuals

NOW Sports - Nutrition and Wellness

A

Zotezo review

The NOW Supplements Silymarin Milk Thistle Extract provides double-strength support for liver function with the added benefits of artichoke and dandelion. While it effectively suppresses sweets cravings, appetite, and cravings for alcohol, potential cons include unexpected weight gain and excessive appetite suppression.

Product details

  • Double Strength Silymarin (300 mg per capsule)

  • Vegetarian formula

  • Includes artichoke and dandelion for additional support

  • 200 Veg Capsules

Benefits of NOW Silymarin Milk Thistle Extra...

  • Suppressed sweets cravings

  • Suppressed appetite

  • Suppressed cravings for alcohol

Weaknesses

  • May cause unexpected weight gain

  • Could suppress appetite and cravings

Tips for choosing the right milk thistle supplements for you

Quick label check

Checking the labels is essential when buying the milk thistle supplement or other supplements. When you check the label, you can see the amount of milk thistle used in the product and other compounds present in it. 

Ingredients

When you check the ingredients, you can find if the supplement contains sugar or an allergic component. This makes it easier for you to make the correct choice. The Best Milk Thistle Supplements in USA that our list features are sugar-free and ideal for vegans. 

Customer reviews

Customers always speak the truth. If a supplement is not good enough or doesn’t suit them, they will review negatively. Although we have negated the supplements that had negative reviews, it is beneficial for you to check the reviews to get the idea of the milk thistle supplement.

Type

You should always watch out for the type of milk thistle supplement. Type can be capsule, powder, or liquid. Usually, capsules are a popular choice, but you can go for powder. 

Cost

The price range may vary for different manufacturing companies. Therefore, it is unnecessary if a supplement is expensive, it is the best, or if a supplement is cheaper, it is not the one. Our list consists of the Best Milk Thistle Supplements in USA that suit your requirements.

Brands

The popular brands are popular because more and more people buy the products made from them. The milk thistle supplement with a brand value is always the best because no one will buy it if it is damaged. However, it is advisable to know more about the supplement before buying.

Non-GMO

If the milk thistle supplement is non-GMO, then you can buy it without trouble. Non-GMO products are safe to use without any known side effects.

Quality

Quality is a significant factor that makes one milk thistle supplement different from the other milk thistle supplement. High-quality is always expected from any brand, and you will know that after watching out for customer ratings and seller’s rank.

Organic is not just a word

Always go for the milk thistle supplements that are organic. While checking the label, you can find the word ‘100% organic’. It would be best to always check this label before buying any supplement to avoid the side effects.

Products listed here are carefully reviewed and tested by our expert authors and reviewers. If you buy through links on this page, we may earn a small commission. Here’s our editorial process.

How we reviewed these products

Benefits of using milk thistle supplements

There are lots of benefits of milk thistle supplements. From treating diseases to making diabetic persons fit, we will explore all the advantages of why you should buy this excellent supplement.

Health benefits

The target organ is the liver. As we know, the liver is the largest organ, and our body needs the constant functioning of the liver. Unfortunately, when we see today’s world, foods cannot give the proper nutrition that a body requires to maintain health. So, milk thistle supplement is a healthy derivative to help you become stronger.

Anti-inflammatory and antioxidant properties

These properties help you get glowing skin and a healthy body. It also fastens the pain relief. In addition, a healthy liver increases the metabolism that makes you fit when there is a healthy liver. 

Helps in preventing cancer

Milk thistle seed has an antioxidant flavonoid, silymarin, that may help in reducing the cancer development risk by enhancing the immune system’s capacity, protecting DNA damage, and reversing the growth of cancerous cells. As a result, it can prevent and help cure breast cancer, lung cancer, prostate cancer, and other tumors.

Around fifty percent of the silymarin molecules are called silybin or silibinin. This antioxidant initiates protein synthesis and protects the healthy cells from damage and mutation by changing their outside layers. It also can inhibit toxins from harming the body and also helps cells to rejuvenate and counteract with pollutants, chemicals, heavy metals, etc.

Aids in lowering high cholesterol

As we have told you, milk thistle helps deal with liver issues. In addition, high cholesterol is curbed by milk thistle by reducing inflammation, cleaning the blood, and preventing free radical damage within the arteries.

Helps in curing diabetes

Research on milk thistle suggests that it can help in treating diabetes because it has the capability of normalizing or maintaining healthy blood glucose levels. Therefore, type 2 diabetes is targeted by milk thistle. In addition, the best milk thistle supplements in USA are sugar-free, making them risk-free.

Prevents gallstones

Milk thistle can help prevent gallstones and kidney stones because the liver and other digestive organs like the gallbladder, pancreas, intestines, and kidneys work together to improve liver health.

Milk thistle may help prevent gallstones because of its ability to increase bile flow, protect against liver conditions like nonalcoholic fatty liver disease, and promote liver detoxification.

When cholesterol and other matter in your bile bind together, gallstones form. This is problematic because they can solidify and become lodged in your gallbladder’s inner lining.

May prevent aging

Due to antioxidants that engulf the free radicals, the monsters causing oxidative stress and dull skin, milk thistle helps prevent aging. In addition, antioxidants can protect your body from chronic diseases on the surface of your skin and inside your organs. The Best Milk Thistle Supplements in USA can provide you with the benefits that you desire. So get your hands on the best milk thistle included in our list.

Side-effects of using Milk Thistle Supplements

Certain types of allergies, swelling on lips and tongue, headache, indigestion, diarrhea, loss of appetite, and hormonal problems are heard from the people who experienced side effects from milk thistle supplements. Therefore, it would be best to ask your health practitioner before taking milk thistle.

  • For the treatment of the liver, the dose has to be 280 mg per day. 
  • For diabetic treatment, the quantity could be 200mg thrice per day.

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Frequently asked questions on milk thistle supplements

1. What contributes to the durability of milk thistle supplements?

2. What are the chances of having a side effect from milk thistle supplements?

3. Is milk thistle supplement worth buying?

4. Can I get a milk thistle supplement in liquid form?

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Conclusion

Buying the Best Milk Thistle Supplements in USA could be a cumbersome task alone, but we have tried our best to make the job easier for you. You can refer to our buyer’s guide and consider the factors that can help you get hold of the best milk thistle supplement.

Did you find this article interesting? Were these products on your checklist as well? 

Do keep us posted in the comments below and share it with your friends, families and beloved. Also, don’t forget to mention the Best Milk Thistle Supplements in USA that you pick up from the best digital marketplace.

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Dt. Stacy Gulbin

RD, M.Ed., MS

Dietitian verified

Stacy has been a registered dietitian since 2010, She is currently working as an author, and clinical dietitian at Zotezo. She has experience in various fields of nutrition including research, fitness, medical weight loss, long-term care, rehab, and bariatrics. She has also been contributing to various online entities since 2011 including Examiner.com, Livestrong, and Cdiabetes.com