Introduction

Welcome to the world of supplements where we often find ourselves navigating through a jungle of promises and possibilities. In this intriguing landscape, Nicotinamide Riboside (NR) emerges as a captivating compound, garnering attention for its potential health benefits. As a dietitian and author, I invite you to delve into the science, the hype, and the reality surrounding NR supplements.

Nicotinamide Riboside, a form of vitamin B3, has recently captured the spotlight due to its role in cellular energy metabolism and potential anti-aging effects. As we age, our cells experience a decline in NAD+ levels, a coenzyme vital for various biological processes including DNA repair and energy production. NR, by boosting NAD+ levels, has garnered interest for its purported ability to support cellular health and potentially mitigate age-related decline.

In this article, we’ll explore the origins of NR, its mechanisms of action, and the scientific evidence behind its touted benefits. We’ll also address important considerations such as safety, dosage, and its potential interactions with medications or existing health conditions.

Nicotinamide Riboside Supplements in India

Our pick of the 7 best Nicotinamide Riboside Supplements of 2024 in India

Zotezo Score
Best Nicotinamide Riboside Supplements
Lowest Price

B+

Rs.13,975.00

Rs.13,100.00

B+

Rs.5,999.00

Rs.4,199.00

B

Rs.2,800.00

Rs.1,290.00

B

Rs.4,000.00

Rs.2,999.00

B

Rs.1,499.00

Rs.786.00

C+

Rs.5,499.00

Rs.2,599.00

C

Rs.3,199.00

Rs.1,799.00

Let's take a deep dive into these 7 best Nicotinamide Riboside Supplements in India

Best Overall Nicotinamide Riboside Supplements in India

Thorne Research

B+

Zotezo review

The Thorne Research Methyl-Guard Plus, 90 Capsules is a dietary supplement officially imported, offering 90 capsules per pack. While it provides essential nutrients, some may find the higher price point and potential dietary restrictions to be drawbacks.

Product details

  • 90 Capsules

  • Officially Imported

  • Dietary Supplement

  • Variable packing and labeling

Benefits of Thorne Methyl-Guard Plus Capsules

  • Contains 90 capsules

  • Officially imported

  • Dietary supplement

Drawbacks

  • Higher price point

  • May not be suitable for individuals with certain dietary restrictions

B+

Zotezo review

The Life Extension NAD+ Cell Regenerator Nicotinamide Riboside Capsules offer an advanced defense against cellular aging and may improve energy levels. However, the limited quantity of capsules per bottle and concerns about product authenticity and quality assurance may be drawbacks to consider.

Product details

  • Dietary supplement

  • Advanced defense against cellular aging

  • Preserves cognitive function during aging

Benefits of Life Extension NAD+ Regenerator ...

  • May help improve energy levels

  • Contains NAD+, a beneficial coenzyme

  • Easy to take in capsule form

Weaknesses

  • Limited quantity of capsules per bottle (30 count)

  • Uncertainty regarding product authenticity and quality assurance

B

Zotezo review

The Fitness Veda NICOTINAMIDE(NMN) supplement offers antioxidant properties, boosts NAD+ levels, and supports cardiovascular health. However, its effectiveness and absence of metformin for an optimal combination are noted as potential drawbacks.

Product details

  • Antioxidant properties

  • Boosts NAD+ levels

  • Regulates blood pressure

  • Supports cardiovascular health

Benefits of Fitness Veda NMN Supplement R...

  • Contains a combination of key ingredients

  • Supports NAD+ levels

  • Antioxidant properties

Disadvantages

  • Unclear effectiveness

  • Missing metformin for optimal combination

B

Zotezo review

Decode Age NMN Pro Uthever 1000 offers ultra-pure NMN with proven benefits such as slowing down aging, cellular repair, and boosting Nad+. The product stands out for its high-quality natural ingredients, energy-boosting properties, and convenient dosage, although it comes at a higher price point and with limited quantity per bottle compared to other options on the market.

Product details

  • Ultra-Pure NMN

  • Slow Down Ageing

  • Cellular Repair

  • Boost Nad+

  • Kosher Certified

  • Human Clinical Trial Conducted

Benefits of Age Decode NMN Pro Uthever 1000

  • High quality natural ingredients

  • Boosts energy levels

  • Improves mental focus

  • Enhances skin elasticity

  • Supports physical performance

  • Convenient dosage and administration

Negatives

  • Limited quantity in each bottle

  • Higher price point than similar products

B

Zotezo review

The Humming Herbs Quercetin Supplement – NMN plus Resveratrol Extract – 90 Capsules is a potent blend that supports anti-inflammatory response, immune system, cardiovascular health, and healthy aging. While some users may find the price high and not suitable for immediate results, its strong and effective formula containing Quercetin, NMN, and Resveratrol supports blood vessels and overall health.

Product details

  • Quercetin, NMN extract, and resveratrol blend

  • Supports anti-inflammatory response

  • Supports immune system

  • Benefits cardiovascular health

  • Supports healthy aging

Benefits of HerbHum Quercetin – NMN Re...

  • Strong and effective formula

  • Contains Quercetin, NMN, and Resveratrol

  • Supports blood vessels and overall health

Cons

  • Not suitable for those looking for immediate results

  • Some users may find the price high, especially when not on sale

Vitagenics Lifesciences

C+

Zotezo review

The StemRx Biosciences NMN-NAD supplement offers an advanced anti-aging formula and boosts muscle strength with its Nicotinamide Mononucleotide content. While it may take time to see results and the quantity in one bottle is limited, the scientifically backed ingredients make it a promising choice for those seeking vitality and improved muscle health.

Product details

  • Advanced anti-aging formula

  • Revitalizes vitality

  • Scientifically backed ingredients

  • Enhances muscle strength

  • Contains Nicotinamide Mononucleotide

  • 60 veg capsules

Benefits of StemRx NMN-NAD Anti-Aging Supple...

  • Advanced anti-aging formula

  • Enhances muscle strength

  • Contains Nicotinamide Mononucleotide

Drawbacks

  • Takes time to see results

  • Limited quantity in one bottle

C

Zotezo review

This NMN Nicotinamide Mononucleotide Supplement offers fast delivery, an energy and focus boost, and an affordable price. However, customers may find the inverted cover on the bottle and non-English reviews as drawbacks.

Product details

  • NAD+ booster

  • Anti-aging support

  • Cellular energy enhancement

  • Metabolism support

  • DNA repair

  • Contains 30 capsules

Benefits of NMN Supplement – Anti-Agin...

  • Fast delivery

  • Energy and focus boost

  • Affordable price

  • Genuine and pure product

Weaknesses

  • Inverted cover on bottle

  • Non-English reviews present

Tips for choosing the right Nicotinamide Riboside Supplements for you

Navigating the world of supplements can feel like embarking on a labyrinthine journey, especially when exploring the realm of Nicotinamide Riboside (NR) supplements. As a dietitian and author, I understand the importance of making informed choices when it comes to selecting supplements for optimal health. In this comprehensive buyer’s guide, we’ll unravel the intricacies of NR supplements, examining various types, certifications, ingredients, sources, and other pertinent factors to consider before making your purchase.

Types of Nicotinamide Riboside Supplements:

When exploring NR supplements, you’ll encounter different formulations tailored to suit diverse preferences and dietary needs. Capsules, softgels, powders, and liquid formulations are among the most common types available in the market. Each format offers unique advantages, ranging from convenience to enhanced absorption rates. Capsules and softgels are popular choices for their ease of consumption and precise dosage measurements, while powders and liquids offer flexibility in dosage customization and absorption rates.

Certifications and Quality Standards:

Prioritizing quality and safety is paramount when selecting NR supplements. Look for products that adhere to rigorous quality standards and are certified by reputable third-party organizations such as NSF International, USP (United States Pharmacopeia), or ConsumerLab.com. These certifications ensure that the supplements meet stringent criteria for purity, potency, and absence of contaminants.

Ingredients to Look For:

When scrutinizing the ingredient list of NR supplements, prioritize products formulated with high-quality, bioavailable Nicotinamide Riboside. Opt for supplements that contain minimal fillers, additives, or artificial ingredients. Additionally, consider products that incorporate synergistic compounds such as resveratrol or pterostilbene, which may enhance the bioavailability and efficacy of NR.

Avoid Harmful Ingredients:

Exercise caution and vigilance when assessing the ingredient list of NR supplements, steering clear of potentially harmful additives or allergens. Be wary of supplements containing artificial colors, flavors, preservatives, or common allergens such as gluten, soy, or dairy. Additionally, avoid products that contain excessive amounts of fillers or bulking agents, which may compromise the purity and potency of the supplement.

Sources of Nicotinamide Riboside:

Nicotinamide Riboside can be sourced from various natural sources, including dairy products, yeast, and certain vegetables. However, NR supplements are primarily derived from synthetic or bioengineered sources to ensure consistency and purity. When selecting NR supplements, prioritize products sourced from reputable manufacturers known for their commitment to quality and transparency in sourcing and production practices.

Dosage and Usage Guidelines:

Determining the appropriate dosage of NR supplements requires careful consideration of individual factors such as age, health status, and specific health goals. While there is no universally recommended dosage for NR, clinical studies suggest that doses ranging from 100 mg to 1000 mg daily are well-tolerated and may confer health benefits. However, it’s advisable to start with a lower dosage and gradually titrate upwards while monitoring for any adverse effects or interactions with medications.

Consultation with Healthcare Professionals:

Before incorporating NR supplements into your regimen, it’s essential to consult with a qualified healthcare professional, especially if you have pre-existing medical conditions or are taking medications. Your healthcare provider can offer personalized guidance based on your unique health profile, ensuring safe and effective supplementation.

Consideration of Potential Interactions:

Nicotinamide Riboside supplements may interact with certain medications or supplements, necessitating caution and careful monitoring. Consult with your healthcare provider to assess potential interactions with medications such as blood thinners, diabetes medications, or chemotherapy drugs. Additionally, consider potential interactions with other supplements or herbs to avoid adverse effects or diminished efficacy.

Transparency and Accountability:

When evaluating NR supplement brands, prioritize companies that demonstrate transparency and accountability in their sourcing, manufacturing, and quality control practices. Look for brands that provide comprehensive information regarding their sourcing of raw materials, manufacturing processes, and quality assurance measures. Additionally, seek out brands that undergo independent third-party testing to verify the purity, potency, and safety of their products.

Consumer Reviews and Feedback:

Harness the power of consumer reviews and feedback to glean insights into the efficacy and quality of NR supplements. Explore reputable online platforms and forums where consumers share their firsthand experiences and opinions regarding various supplement brands. Pay attention to recurring themes and patterns in consumer feedback, focusing on factors such as product effectiveness, taste, and customer service.

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Benefits of using Nicotinamide Riboside Supplements

Nicotinamide Riboside (NR) supplements have been generating buzz in health and wellness circles for their potential to support various aspects of health and vitality. As a dietitian and author, I’m eager to explore the intriguing science behind NR supplementation and uncover the potential health benefits it may offer.

Cellular Energy Production:

At the heart of Nicotinamide Riboside’s appeal lies its role in cellular energy metabolism. NR serves as a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for numerous biochemical reactions within the body, including the conversion of nutrients into cellular energy. As we age, NAD+ levels naturally decline, contributing to age-related declines in cellular function and metabolism. By supplementing with NR, individuals may support optimal NAD+ levels, enhancing cellular energy production and metabolic efficiency.

Mitochondrial Function and Anti-Aging:

Mitochondria, often referred to as the “powerhouses” of the cell, play a pivotal role in energy production and cellular function. Nicotinamide Riboside has been shown to support mitochondrial health and function, thereby potentially mitigating age-related decline and promoting longevity. By bolstering mitochondrial biogenesis and enhancing mitochondrial respiration, NR supplementation may contribute to improved energy levels, enhanced physical performance, and overall vitality.

DNA Repair and Cellular Integrity:

Another compelling aspect of NR supplementation lies in its potential to support DNA repair mechanisms and maintain cellular integrity. NAD+ serves as a crucial cofactor for enzymes involved in DNA repair pathways, helping to safeguard against DNA damage and mutations. By replenishing NAD+ levels, NR supplements may enhance the body’s ability to repair damaged DNA, mitigate oxidative stress, and promote cellular longevity.

Cardiovascular Health:

Emerging research suggests that Nicotinamide Riboside supplementation may confer benefits for cardiovascular health and function. NAD+ plays a critical role in regulating vascular tone, endothelial function, and cardiovascular homeostasis. By promoting NAD+ synthesis, NR supplements may help support healthy blood flow, endothelial function, and cardiovascular resilience. Additionally, NR’s anti-inflammatory properties and ability to mitigate oxidative stress may further contribute to cardiovascular protection and overall heart health.

Metabolic Health and Weight Management:

Maintaining optimal metabolic health is essential for overall well-being and disease prevention. Nicotinamide Riboside supplements may offer promising implications for metabolic health and weight management by enhancing mitochondrial function, promoting energy expenditure, and optimizing metabolic efficiency. NR supplementation has been linked to improvements in insulin sensitivity, glucose metabolism, and lipid profiles, making it a potential adjunctive therapy for individuals seeking to support their metabolic health and achieve weight management goals.

Cognitive Function and Brain Health:

The brain, with its high energy demands and susceptibility to oxidative stress, stands to benefit from Nicotinamide Riboside supplementation. NAD+ plays a crucial role in neuronal health, synaptic plasticity, and cognitive function. By supporting NAD+ levels, NR supplements may help preserve cognitive function, enhance memory retention, and mitigate age-related cognitive decline. Additionally, NR’s neuroprotective properties and ability to modulate neuroinflammatory pathways hold promise for promoting brain health and resilience against neurodegenerative diseases.

Exercise Performance and Recovery:

For individuals seeking to optimize their athletic performance and recovery, Nicotinamide Riboside supplements may offer a valuable ally. NR supplementation has been shown to enhance mitochondrial biogenesis, improve muscle endurance, and facilitate faster recovery from exercise-induced fatigue. By bolstering cellular energy production and mitigating oxidative stress, NR supplements may help athletes and fitness enthusiasts maximize their performance potential, recover more efficiently, and sustain peak physical vitality.

Skin Health and Anti-Aging:

The skin, as the body’s largest organ, is constantly exposed to environmental stressors and oxidative damage. Nicotinamide Riboside supplementation may support skin health and anti-aging by promoting cellular repair mechanisms, enhancing collagen synthesis, and mitigating oxidative stress. NAD+ plays a critical role in DNA repair pathways within skin cells, helping to maintain skin integrity and resilience against photoaging and environmental aggressors. By replenishing NAD+ levels, NR supplements may contribute to a more youthful complexion, improved skin texture, and enhanced overall skin health.

Side-effects of using Nicotinamide Riboside Supplements

While Nicotinamide Riboside (NR) supplements hold promise for enhancing health and vitality, it’s important to acknowledge the potential for side effects and adverse reactions, particularly in certain individuals or under specific circumstances.

Gastrointestinal Disturbances: Some individuals may experience gastrointestinal discomfort or disturbances when first starting Nicotinamide Riboside supplementation. Symptoms such as nausea, abdominal cramping, diarrhea, or bloating may occur, especially at higher doses or in sensitive individuals. These side effects are often transient and may subside as the body adjusts to the supplement. Starting with a lower dosage and gradually increasing intake can help mitigate gastrointestinal discomfort.

Potential Interactions with Medications: Nicotinamide Riboside supplements may interact with certain medications, potentially altering their efficacy or increasing the risk of adverse effects. Individuals taking medications such as blood thinners, diabetes medications, or chemotherapy drugs should exercise caution and consult with a healthcare professional before starting NR supplementation. Additionally, individuals with pre-existing medical conditions or those taking other supplements should seek guidance from a healthcare provider to minimize the risk of interactions.

Allergic Reactions: In rare cases, individuals may experience allergic reactions to Nicotinamide Riboside supplements or other ingredients used in their formulation. Allergic reactions may manifest as skin rashes, itching, swelling, or difficulty breathing. If you experience any signs of an allergic reaction after taking NR supplements, discontinue use immediately and seek medical attention.

Impact on Blood Sugar Levels: Nicotinamide Riboside supplementation may affect blood sugar levels, particularly in individuals with diabetes or insulin resistance. While some studies suggest that NR may improve insulin sensitivity and glucose metabolism, others indicate that it may lower blood sugar levels, potentially leading to hypoglycemia in susceptible individuals. Individuals with diabetes should monitor their blood sugar levels closely when initiating NR supplementation and consult with a healthcare provider to adjust medication dosages as needed.

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Conclusion

In conclusion, Nicotinamide Riboside supplements present a fascinating avenue for those seeking to optimize their health and vitality. As we’ve explored throughout this article, NR supplements offer a promising array of potential benefits, ranging from supporting cellular energy production and mitochondrial function to promoting cardiovascular health, cognitive function, and metabolic resilience. With their ability to replenish NAD+ levels and activate key pathways involved in cellular repair and rejuvenation, NR supplements have garnered attention for their role in mitigating age-related decline and promoting longevity.

However, it’s essential to approach Nicotinamide Riboside supplementation with a balanced perspective, acknowledging both the potential benefits and the potential risks. While NR supplements are generally well-tolerated, some individuals may experience side effects such as gastrointestinal disturbances, interactions with medications, allergic reactions, or fluctuations in blood sugar levels. By staying informed, starting with conservative dosages, and seeking guidance from healthcare professionals, individuals can navigate the use of NR supplements safely and effectively.

Furthermore, it’s important to recognize that Nicotinamide Riboside supplementation is just one piece of the wellness puzzle. Optimal health and vitality encompass a holistic approach that includes regular physical activity, a balanced diet rich in nutrients, adequate sleep, stress management techniques, and meaningful social connections. NR supplements should complement, rather than replace, these foundational elements of a healthy lifestyle.

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Dt. Stacy Gulbin

RD, M.Ed., MS

Dietitian verified

Stacy has been a registered dietitian since 2010, She is currently working as an author, and clinical dietitian at Zotezo. She has experience in various fields of nutrition including research, fitness, medical weight loss, long-term care, rehab, and bariatrics. She has also been contributing to various online entities since 2011 including Examiner.com, Livestrong, and Cdiabetes.com