What is Selenium?

Selenium is a trace mineral that plays an essential role in maintaining overall health and well-being. It is found in a variety of foods, including seafood, meat, grains, and dairy products. Selenium is a powerful antioxidant, which means it helps protect cells from damage caused by harmful molecules called free radicals.

One of the most important functions of selenium is its role in supporting the body’s immune system. It helps strengthen the immune response and promotes the production of antibodies, which are essential for fighting off infections and diseases.

Selenium also plays a crucial role in thyroid function. It is necessary for the production of thyroid hormones, which help regulate metabolism and energy production. Inadequate selenium intake can lead to thyroid dysfunction and may contribute to conditions such as hypothyroidism.

To ensure adequate selenium intake, it is important to include selenium-rich foods in your diet. Good sources of selenium include Brazil nuts, seafood (such as oysters, tuna, and shrimp), poultry, eggs, whole grains, and dairy products.

What are the benefits of Selenium?

Selenium is a trace mineral that plays a crucial role in various physiological functions within the human body. Discovered in 1817 by the Swedish chemist Jöns Jacob Berzelius, selenium was initially considered toxic at high doses. However, as research progressed, it became evident that selenium is an essential micronutrient vital for human health.

Antioxidant Properties: Selenium is a key component of antioxidant enzymes like glutathione peroxidase, which helps neutralize harmful free radicals in the body, thereby protecting cells and tissues from oxidative damage.

Thyroid Function: Selenium is necessary for the conversion of the thyroid hormone thyroxine (T4) to its active form, triiodothyronine (T3). Adequate selenium levels support optimal thyroid function and metabolism.

Immune System Support: Selenium plays a critical role in supporting the immune system by enhancing the activity of immune cells and promoting the production of cytokines, which are important for immune response regulation.

Cancer Prevention: Some studies suggest that selenium may help reduce the risk of certain cancers, including prostate cancer, colorectal cancer, and lung cancers. Selenium’s antioxidant properties and its role in DNA repair mechanisms contribute to its potential anticancer effects.

Heart Health: Selenium may have benefits for heart health by reducing inflammation, improving blood flow, and preventing oxidative damage to blood vessels.

Cognitive Function: Preliminary research suggests that selenium may play a role in supporting cognitive function and reducing the risk of cognitive decline with aging.

What are the Side-effects of Selenium?

While selenium is essential for health, excessive intake can lead to selenium toxicity, known as selenosis. Symptoms of selenium toxicity may include gastrointestinal disturbances, hair loss, nail brittleness, fatigue, and neurological abnormalities. Chronic selenium toxicity can lead to more severe health issues and should be avoided.

What are the various types of Selenium?

Selenium exists in several forms, including selenomethionine, selenocysteine, selenium dioxide, and selenite. Among these forms, selenomethionine is the most common organic form found in foods, while selenite and selenium dioxide are often used in supplements and fortified foods.

Selenomethionine is a naturally occurring amino acid that incorporates selenium into proteins, whereas selenocysteine is a rare amino acid found in selenoproteins, which are enzymes that require selenium for their activity.

How does Selenium work?

Selenium exerts its biological effects primarily through selenoproteins, which are a group of proteins containing the amino acid selenocysteine. These selenoproteins serve various functions in the body, including antioxidant defense, thyroid hormone metabolism, DNA synthesis and repair, immune function, and fertility.

One of the most well-known selenoproteins is glutathione peroxidase, which catalyzes the reduction of hydrogen peroxide and organic hydroperoxides, protecting cells and tissues from oxidative damage. Other selenoproteins include thioredoxin reductase, which regulates cellular redox balance, and iodothyronine deiodinases, which play a role in thyroid hormone metabolism.

Selenium also interacts with other antioxidants, such as vitamin E, synergistically enhancing their antioxidant activity and contributing to overall cellular protection against oxidative stress.

Recommended dosage of Selenium

The recommended dietary allowance (RDA) for selenium varies depending on age, sex, and life stage. The RDA for selenium for adults is 55 micrograms per day for both men and women. Pregnant and breastfeeding women may require slightly higher amounts of selenium to support fetal growth and lactation.

While selenium deficiency is rare in well-nourished populations, individuals with certain health conditions or dietary restrictions may be at risk of inadequate selenium intake. In such cases, supplementation under the guidance of a healthcare professional may be warranted to ensure optimal selenium status.

It’s important to emphasize that obtaining selenium through a balanced diet rich in selenium-containing foods, such as Brazil nuts, seafood, poultry, eggs, and whole grains, is generally preferred over supplementation. Dietary sources provide selenium in forms that are more readily absorbed and utilized by the body, minimizing the risk of toxicity associated with high-dose supplements.

Natural and Food Sources of Selenium

There are several food sources that are rich in selenium. One of the best sources is Brazil nuts. Just a few of these nuts a day can easily provide your daily selenium needs. Other nuts, such as cashews and peanuts, along with seeds like sunflower and chia seeds, are also good sources. Whole grains like brown rice, oats, and wheat germ, as well as legumes like lentils and chickpeas, are great options for those following a plant-based diet.

When it comes to animal sources, seafood stands out. Fish such as tuna, salmon, sardines, and halibut are excellent sources of selenium. Other animal-based options include chicken, turkey, pork, beef, and eggs. Including a variety of these foods in your diet can help ensure an adequate intake of selenium.

Frequently Asked Question on Selenium

Q: What is selenium?

Selenium is a mineral that is essential for our bodies in small amounts. It plays a crucial role in various physiological processes, including metabolism and thyroid function.

Q: What are the dietary sources of selenium?

Dietary sources of selenium include Brazil nuts, fish (such as tuna, sardines, and salmon), shellfish, poultry (chicken and turkey), eggs, beef, liver, and whole grains.

Q: Can I get enough selenium from my diet alone?

It is possible to meet your selenium needs through diet alone, especially if you consume a varied and balanced diet that includes selenium-rich foods. However, the selenium content of foods can vary depending on the soil in which they were grown, so supplementation may be necessary in some cases.

Q: What happens if I don’t get enough selenium?

Selenium deficiency is rare in well-nourished individuals who consume a balanced diet. However, in cases of severe deficiency, symptoms may include muscle weakness, fatigue, hair loss, and weakened immune function.

Q: Can selenium supplements help prevent cancer?

The relationship between selenium supplementation and cancer prevention is complex and still not well understood. While some studies have suggested a potential protective effect, others have found no significant benefits. More research is needed to fully understand the role of selenium in cancer prevention.

Q: Can selenium supplements improve fertility?

Some research suggests that selenium supplementation may have a positive impact on fertility, particularly in men. Selenium plays a role in sperm formation, motility, and overall sperm quality. However, more research is needed to establish clear recommendations for selenium supplementation in fertility.

Q: Should I take selenium supplements if I have a thyroid condition?

If you have a thyroid condition, such as hypothyroidism or Hashimoto’s thyroiditis, it is best to consult with a healthcare professional before taking selenium supplements. Selenium plays a role in thyroid function, and supplementation may be beneficial in some cases. However, individual needs can vary, and it is important to receive personalized recommendations based on your specific condition.

Q: Can selenium supplements improve my skin?

Selenium is involved in skin health and can act as an antioxidant, protecting our cells from damage. Some studies have shown associations between selenium levels and skin health, but more research is needed to determine the specific effects of selenium supplementation on the skin.

Q: Can selenium supplements benefit my hair and nails?

Selenium is important for healthy hair and nails. Adequate selenium levels support the growth and strength of hair and nails. However, it is important to maintain a balanced diet and overall healthy lifestyle for optimal hair and nail health.

Q: Can selenium help with mood or depression?

Research on the relationship between selenium and mood is limited. Some studies have suggested a potential link between low selenium levels and depressive symptoms, but more research is needed to fully understand the relationship and the potential benefits of selenium supplementation for mood.

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Dr. Heather Smith

MD, FRCP

Medical Practitioner verified

By day I’m a critical care physician and medical leader. By night I’m the mom of 2 chaotic, wonderful boys. Somewhere in the middle of all that, I’m building a skincare brand and trying to save the world from plastic waste.