Introduction

The grape seed extract is a dietary supplement created from the seeds of grapes. It is a rich source of antioxidants, particularly proanthocyanidins. The antioxidants in the best grape seed extract supplements in Italy may help relieve oxidative stress, inflammation, and tissue injury that can appear alongside chronic diseases.

Most of these health claims are still not supported by credible studies, but some evidence supports their use. The grape seed extract is available as a dietary supplement in a liquid form, tablets, or capsules. Supplements generally contain 50 to 100 milligrams (mg) of grape seed extract.

Studies on animal models have shown that grape seed extract can be beneficial in treating heart disease. Some experts think grape seed extract could even include anticancer and cancer chemopreventive possibilities. Over recent years, there has been a great deal of research suggesting the therapeutic properties of grape seed extract.

Check out our list of the best grape seed extract supplements in Italy to find the one you are in search of.

Grape Seed Extract Supplements in Italy

Our pick of the 6 best grape seed extract supplements of 2024 in Italy

Zotezo Score
Best Grape Seed Extract Supplements
Lowest Price

B+

€24.97

€20.97

B+

€28.55

€28.55

B+

€17.99

€17.99

B

€11.95

€11.95

B

€77.20

€77.20

C+

€14.90

€14.90

Let's take a deep dive into these 6 best Grape Seed Extract Supplements in Italy

Best Overall Grape Seed Extract Supplements in Italy

Vitamaze - amazing life

B+

Zotezo review

The OPC Estratto di Semi D’Uva Capsule + Vitamina C is a highly dosed dietary supplement made in Germany, containing 450 mg of pure OPC and 100 mg of Vitamin C per capsule. With 180 capsules, it provides 6 months of continuous use. Customers have expressed satisfaction with the product’s quality and effectiveness.

Product details

  • Highly dosed with 450 mg of pure OPC per capsule

  • Contains 100 mg of Vitamin C for physiological optimization

  • 180 capsules for 6 months of continuous use

  • Made in Germany

  • Natural dietary supplement without additives

Benefits of OPC Grape Seed Extract Capsules ...

  • Highly dosed with 450 mg of pure OPC per capsule

  • Contains 100 mg of Vitamin C for physiological optimization

  • 180 capsules for 6 months of continuous use

  • Made in Germany

Drawbacks

  • No specific drawbacks were mentioned in the reviews

  • Customers mentioned that they have been repeat buyers of the product, indicating their satisfaction with its quality and effectiveness

B+

Zotezo review

The “Estratto di Semi d’uva 2000 mg – 360 compresse – Adatto ai vegani – 6 mesi di durata – SimplySupplements” is a vegan-friendly product that contains 2000 mg of Grape Seed Extract and Vitamin C for enhanced effects. It offers a six-month supply and has positive reviews for improving circulation and reducing water retention. However, some users may find the rapid growth of nails and darkening of hair as undesirable side effects.

Product details

  • Contains 2000 mg of Grape Seed Extract

  • Includes Vitamin C for enhanced effects

  • 360 tablets per package

  • Suitable for vegans

  • Six-month supply

  • Supports overall health and well-being

Benefits of Grape Seed Extract 2000mg –...

  • Suitable for vegans

  • 6 months of durability

  • Positive reviews for improving circulation and reducing water retention

Weaknesses

  • The rapid growth of nails may be an undesirable side effect for some users

  • The darkening of hair may not be desired by those who prefer their natural hair color

B+

Zotezo review

The OPC ad Alto Dosaggio – 240 Capsule Vegan di Estratto Semi Uva Francese (8 Mesi) is a highly recommended supplement due to its high dosage of OPC, vegan-friendly and certified ingredients, and highly bioavailable formulation. However, it may have limited availability in certain regions and the packaging could be improved for user convenience.

Product details

  • High Dosage OPC: The product offers a high dosage of OPC (oligomeric proanthocyanidins) in each capsule, providing a potent and concentrated dose. This ensures that users can benefit from the full range of antioxidant and anti-inflammatory properties that OPC offers

  • Vegan and Certified: The OPC ad Alto Dosaggio is a vegan-friendly supplement, making it suitable for individuals following a plant-based lifestyle. Additionally, the product is certified, guaranteeing its quality, purity, and adherence to strict manufacturing standards

  • Highly Bioavailable: The OPC supplement is formulated using a highly bioavailable extract from French grape seeds. This allows for optimal absorption by the body, ensuring that users can experience the maximum benefits of the flavonoids and antioxidants present in grape seeds

Benefits of OPC High Dosage – 240 Vega...

  • High dosage of OPC

  • Vegan and certified

  • Highly bioavailable

Disadvantages

  • Limited availability in some regions

  • Packaging could be more user-friendly

B

Zotezo review

The Fair & Pure® – OPC 500mg – Grape Seed Extract – Vegan – 60 Capsule is a high-quality product with a high concentration of OPC and a vegan formulation. However, some customers have experienced delays in delivery and have found the packaging to be poor.

Product details

  • OPC 500mg from grape seed extract

  • Proanthocyanidins oligomeric in nature

  • Vegan formulation

  • 60 capsules per bottle

  • Gluten, fructose, and lactose-free

  • No magnesium stearate, silicon dioxide, colorants, flavors, or preservatives

Benefits of Fair & Pure® OPC 500mg ̵...

  • High concentration of OPC (500mg)

  • Vegan formulation

  • Free from gluten, fructose, lactose and harmful additives

Negatives

  • Delay in delivery

  • Poor packaging

B

Zotezo review

The Grape Seed Extract 300mg x 720 tablets by Pureclinica is a highly effective product for reducing the signs of varicose veins, thanks to its high concentration of 90% Oligomeric Proanthocyanidins. With a dosage that is 300% stronger than regular Grape Seed extracts, it provides a powerful solution for those seeking relief. However, customers should be aware that immediate results may not be seen and the product may not be suitable for individuals with certain medical conditions.

Product details

  • Grape Seed Extract 300mg per tablet

  • 720 tablets in total (4 bottles of 180 tablets each)

  • Contains 90% Oligomeric Proanthocyanidins

  • 300% stronger than regular Grape Seed extracts

Benefits of Pureclinica Grape Seed Extract 3...

  • Effective in reducing the signs of varicose veins

  • High concentration of Oligomeric Proanthocyanidins

  • Provides a stronger dosage compared to regular Grape Seed extracts

Cons

  • Some customers may not see immediate results

  • The product may not be suitable for individuals with certain medical conditions

C+

Zotezo review

Bandini® Integratore OPC (95%) Estratto di semi d’uva con Vitamina C is a good quality product with natural and safe ingredients, offered at a competitive price. However, some users have reported a strong odor that resembles mold, which could be a drawback for certain customers.

Benefits of Bandini® OPC Integratore –...

  • Good quality product

  • Competitive price compared to similar products

  • Natural and safe ingredients

Drawbacks

  • Some users have reported a strong odor, resembling mold, which may be off-putting to some customers

  • No additional drawbacks mentioned in the reviews

Tips for choosing the right grape seed extract supplements for you

Dose

Dose forms a critical part while choosing the grape seed extract supplement. Therefore, you need to get a good understanding of how much supplement intake you should do.

It depends on your body conditions and your requirements. For example, pregnant women should avoid taking grape seed supplements.

Brand

Choosing the best brand helps you get the best quality. For example, if you want to use the best grape seed extract supplements in Italy, you should keep your faith in the most reputed brand.

Price

Keep in mind that the highest-priced grape seed extract is not always of the best quality. Similarly, the one with the lowest price does not mean that the product is a low-quality one.

So, do not just go with the price. Instead, do proper research before choosing which grape seed extract supplement you wish to buy.

Purpose

You might have a different purpose to use the grape seed extract supplement. Before choosing the grape seed supplement, understand why you want to use it.

It can be used for medicinal purposes, for the betterment of your skin and hair also. The kind of supplement you choose should be able to fulfill your purposes.

Diet type

Vegan diet requirements should also be kept in mind if you are a vegetarian. Dietary requirements should be given importance as you do not want to lose your diet just for the grape seed extract supplements.

Type

What type of grape seed supplement do you want to use? These supplements are available in the form of powder, capsules, and liquid.

You can choose to use any one of them. You get several options to choose the one that meets your comfort level. All the best grape seed extract supplements in Italy featured on our list are available in various types.

 

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Benefits of using grape seed extract supplements

Improve blood flow

Some studies indicate that grape seed extract may improve blood flow. For example, in an 8-week study in 17 healthy postmenopausal women, taking 400 mg of grape seed extract had blood-thinning effects, reducing the risk of blood clots.

An additional study in 8 healthy young women evaluated the effects of a single 400-mg dose of proanthocyanidin from the best grape seed extract supplements in Italy instantly followed by 6 hours of sitting. It helps in relieving leg swelling and edema by 70%, compared with not taking grape seed extract.

Strengthen bone 

Including grape seed extract in your diet with calcium has a significant effect on bone formation and bone strength for the remedy of bone debility caused by a low level of calcium.

Improve kidney function

Your kidneys are particularly sensitive to oxidative damage, which is usually irreversible.

In one study, 23 people having chronic renal failure were given 2 grams of grape seed extract daily for 6 months and then analogised with a placebo group. As a result, urinary protein reduced by 3%, and kidney filtration improved by 9%.

This indicates that the kidneys of those in the test group were much better able to filter urine than the kidneys of those in the placebo group.

Inhibit infectious growth

The best grape seed extract supplements in Italy have antibacterial and antifungal properties. Studies have indicated that grape seed extract inhibits the development of common foodborne bacteria, including Campylobacter and E. coli, which are often responsible for extreme food poisoning and abdominal upset.

In lab studies, grape seed extract deters 43 strains of antibiotic-resistant Staphylococcus aureus bacteria. Candida is a common yeast-like fungus that can often result in candida overgrowth or thrush. The grape seed extract is widely used in traditional medicine as a treatment for candida.

Lower blood pressure

Several studies have examined the effects of grape seed extract on High blood pressure.

A review of 16 studies including 810 people with increased blood pressure or an elevated risk found that consuming 100–2,000 mg of grape seed extract daily notably reduced systolic and diastolic blood pressure by an average of 6.08 mmHg and 2.8 mmHg, respectively.

Those under 50 years of age with obesity or a metabolic disorder demonstrated the best improvements. The most favourable results came from lower doses of 100–800 mg daily for 8–16 weeks, rather than a single dose of 800 mg or more.

Decrease oxidative damage

A high blood level of LDL cholesterol is a comprehended risk factor for heart disease. The oxidation of LDL cholesterol increases this risk and plays a central role in atherosclerosis or the buildup of fatty plaque in your arteries.

In several animal studies, the best grape seed extract supplements in Italy decrease LDL oxidation initiated by high-fat diets. Additionally, some research in humans indicates similar results.

When 8 healthy people ate a high-fat meal, taking 300 mg of grape seed extract inhibited the oxidation of fats in the blood, compared with a 150% growth seen in those who did not take grape seed extract.

Reduce cancer risk

Grape seeds have proanthocyanidins which might control the development of cancer. However, experts believe that the protective characteristic of proanthocyanidins come with different routes.

It helps reduce oxidative stress and immunosuppression by altering cytokine activity. Still, further research is required to firm up the findings.

Heal your wounds

A grape seed extract has the prospect to increase the speed at that wounds heal.

A study “provided firm evidence to support that topical application of GSPE (Grape Seed Proanthocyanidin Extract) illustrates a feasible and productive approach to support skin wound healing.”

Side-effects of using Grape Seed Extract Supplements

The grape seed extract is normally considered safe. However, side effects may involve headaches, itchy scalp, dizziness, and nausea. People allergic to grapes should not consume grape seed extract. If you have a bleeding problem or high blood pressure, consult your doctor before taking the best grape seed extract supplements in Italy.

If you take any regular medicines, talk to your doctor before you start using grape seed extract. It could interact with drugs like blood thinners, NSAID painkillers (like aspirin, Advil, and Aleve), some heart medicines, cancer treatments, and others.

 

There is no firmly specified dose of grape seed extract. Doses between 100-300 milligrams/day have been used in studies and are prescribed in some European countries. No one knows what the highest safe dose is.

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Conclusion

The best grape seed extract supplement in Italy is an excellent supplement made from the seeds of grapes.

It is a rich source of antioxidants, particularly proanthocyanidins. The antioxidants in grape seed extract may help ease inflammation, tissue damage and oxidative stress that occur alongside chronic diseases.

By taking a grape seed extract supplement, you get the opportunity to keep your heart, brain, kidney, liver, and skin health in the best condition.

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Faye James

Clinical Nutritionist

Nutritionist verified

Experienced Senior Content Designer with an impressive portfolio of collaborations with renowned brands such as Woolworths, Weight Watchers, Fitness First, Barry's, Goodlife and Table of Plenty. Accredited Nutritionist and Cook Book Author, with extensive media coverage in ELLE, Glamour, Harpers Bazaar, Daily Express, Telegraph UK, MailOnline, WHIMN, WHO, New Idea, Girlfriend, Practical Parenting, Kidspot, Good Food, Body and Soul, Prevention, Good Health, Healthy Food Guide, Woman's Weekly, Women's Day, NW, Take 5, TV Week, HELLO! and OK! Author of The Menopause Diet (2023), The Long Life Plan (2018) and creator of The 10:10 Diet (2019). Frequently featured as an expert in Body & Soul, and proud member of Nutrition Council Australia and Associate Member of The Australian Menopause Society.