Introduction

The grape seed extract is a dietary supplement created from the seeds of grapes. It is a rich source of antioxidants, particularly proanthocyanidins. The antioxidants in the best grape seed extract supplements in Japan may help relieve oxidative stress, inflammation, and tissue injury that can appear alongside chronic diseases.

Most of these health claims are still not supported by credible studies, but some evidence supports their use. The grape seed extract is available as a dietary supplement in a liquid form, tablets, or capsules. Supplements generally contain 50 to 100 milligrams (mg) of grape seed extract.

Studies on animal models have shown that grape seed extract can be beneficial in treating heart disease. Some experts think grape seed extract could even include anticancer and cancer chemopreventive possibilities. Over recent years, there has been a great deal of research suggesting the therapeutic properties of grape seed extract.

Check out our list of the best grape seed extract supplements in Japan to find the one you are in search of.

Grape Seed Extract Supplements in Japan

Our pick of the 7 best grape seed extract supplements of 2024 in Japan

Zotezo Score
Best Grape Seed Extract Supplements
Lowest Price

A+

¥2,749.00

¥2,749.00

B+

¥4,300.00

¥4,300.00

B+

¥2,806.00

¥2,806.00

B+

¥1,620.00

¥1,465.00

B+

¥2,890.00

¥2,890.00

C+

¥2,307.00

¥2,307.00

C+

¥420.00

¥420.00

Let's take a deep dive into these 7 best Grape Seed Extract Supplements in Japan

Best Overall Grape Seed Extract Supplements in Japan

Puritans pride

A+

Zotezo review

The Puritan’s Pride Grape Seed Extract is an affordable and convenient nutritional supplement that effectively fights chronic infection and inflammation. With its rapid release capsules, it is a convenient option for those looking to incorporate grape seed extract into their daily routine.

Product details

  • Grape seed oil derived from pressed grape seeds

  • Grape seed extract made from dried and powdered grape seeds

  • Nutritional supplement

  • Rapid release capsules

Benefits of Puritan’s Pride Grape Seed...

  • Effective in fighting chronic infection and inflammation

  • Affordable price

  • Convenient rapid release capsules

B+

Zotezo review

The GNC Herbal Plus Grape Seed Extract 300 mg, 100 Count is a high potency formula that provides antioxidant support and potential cardiovascular benefits. However, some customers may find the taste unpleasant and there have been reports of receiving expired product.

Product details

  • High Potency: GNC Herbal Plus Grape Seed Extract contains 300 mg of grape seed extract per serving, ensuring a high potency formula that provides maximum benefits

  • Antioxidant Support: Grape seed extract is rich in antioxidants, which help protect the body against harmful free radicals and oxidative stress. This can contribute to overall health and well-being

  • Cardiovascular Support: Research suggests that grape seed extract may support cardiovascular health by promoting healthy blood circulation and maintaining normal blood pressure levels, which can have long-term benefits for heart health

Benefits of GNC Herbal Plus Grape Seed Extra...

  • High potency formula with 300 mg of grape seed extract per serving

  • Rich in antioxidants for overall health and well-being

  • Potential cardiovascular support for maintaining healthy blood circulation and blood pressure levels

Weaknesses

  • Unpleasant taste

  • Expired product

B+

Zotezo review

The Healthy Care Grape Seed Extract 12000mg 300 Capsules by Nature’s Care is a beneficial product that supports healthy blood circulation, maintains the health of capillaries, and provides antioxidant protection. However, it may have limited availability and a higher price point.

Product details

  • Assists in maintaining blood flow in the hands, feet, and legs

  • Maintains the health of capillaries

  • May assist in improving blood circulation

  • Supports the health of blood vessels

  • Supports the health of the vascular system

  • Provides antioxidant protection

Benefits of Nature’s Care Grape Seed E...

  • Supports healthy blood circulation

  • Maintains the health of capillaries

  • Provides antioxidant protection

Disadvantages

  • Limited availability

  • Higher price point

B+

Zotezo review

Swanson Grape Seed 380mg is an affordable and trusted product made from high-quality grape seeds. With its 380mg of grape seed extract, it supports overall health and well-being. Additionally, it is suitable for international shipping.

Product details

  • Contains 380mg of grape seed extract

  • Made from high-quality grape seeds

  • Supports overall health and well-being

  • Suitable for international shipping

Benefits of Swanson Grape Seed Extract 380mg

  • Affordable price

  • Trusted quality

  • Suitable for international shipping

B+

Zotezo review

The “[海外直送品] ナウフーズ グレープシード・標準化エキス(100mg) 100カプセル” is a product that contains 100mg of grape seed extract per capsule, along with 320mg of Vitamin C. However, there are no noticeable effects yet and there is a lack of information on potential benefits.

Product details

  • Contains 100mg of grape seed extract

  • Each capsule contains 320mg of Vitamin C

  • Each capsule contains 36mg of Calcium

  • Comes in a pack of 100 capsules

  • Manufactured by NOW company

  • Weighs 90.7g

Benefits of ナウフーズ グレープシード・標準...

  • Contains 100mg of grape seed extract

  • Each capsule contains 320mg of Vitamin C

  • Comes in a pack of 100 capsules

Cons

  • No noticeable effects yet

  • Lack of information on potential benefits

Independently published

C+

Zotezo review

The “Heart Healthy Snacks for Seniors” offers a wide variety of delicious snacks that provide essential nutrients for a healthy heart. While the price may be higher compared to regular snacks and the variety may be limited, the combination of taste and health makes it an ideal choice for seniors looking to improve their cardiovascular health.

Product details

  • Variety of Delicious Snacks: The "Heart Healthy Snacks for Seniors" offers a wide range of 30 delicious snacks, ensuring that seniors can enjoy a diverse selection of treats while maintaining a heart-healthy diet

  • Nutritional Benefits: Each snack is carefully crafted to provide essential nutrients for a healthy heart. Packed with vitamins, minerals, and heart-friendly ingredients, these snacks offer a convenient way for seniors to improve their cardiovascular health

  • Ideal for Taste and Health: These snacks are not only good for your heart, but they also cater to your taste buds. The combination of delicious flavors and heart-healthy ingredients ensures that seniors can satisfy their cravings while making a positive impact on their overall well-being

Benefits of Heart Healthy Snacks for Seniors

  • Wide variety of delicious snacks

  • Nutritional benefits for a healthy heart

  • Combination of taste and health

Drawbacks

  • Limited variety of snacks

  • Price may be higher compared to regular snacks

C+

Zotezo review

The “Heart Healthy Food Cookbook” is a valuable resource for individuals looking to maintain a healthy heart. It offers a wide range of easy and flavorful recipes, low-sodium, low-fat, and diabetic-friendly snack and meal options, and includes a meal plan and two bonuses for extra support. However, it may have a limited variety of recipes and may not cater to specific dietary restrictions or allergies.

Product details

  • The "Heart Healthy Food Cookbook" offers a wide range of easy and flavorful recipes specifically designed to cater to individuals looking to maintain a healthy heart

  • The cookbook provides low-sodium, low-fat, and diabetic-friendly snack and meal recipes, ensuring that individuals can enjoy delicious food while keeping their blood pressure in check

  • In addition to the meal plan, the cookbook also includes two bonuses that offer extra value and support for individuals seeking to adopt a heart-healthy lifestyle

Benefits of Healthy Living Cookbook: Low-Sod...

  • Offers a wide range of easy and flavorful recipes for maintaining a healthy heart

  • Provides low-sodium, low-fat, and diabetic-friendly snack and meal options

  • Includes a meal plan and two bonuses for extra value and support

Weaknesses

  • Limited variety of recipes

  • May not include specific dietary restrictions or allergies

Tips for choosing the right grape seed extract supplements for you

Dose

Dose forms a critical part while choosing the grape seed extract supplement. Therefore, you need to get a good understanding of how much supplement intake you should do.

It depends on your body conditions and your requirements. For example, pregnant women should avoid taking grape seed supplements.

Brand

Choosing the best brand helps you get the best quality. For example, if you want to use the best grape seed extract supplements in Japan, you should keep your faith in the most reputed brand.

Price

Keep in mind that the highest-priced grape seed extract is not always of the best quality. Similarly, the one with the lowest price does not mean that the product is a low-quality one.

So, do not just go with the price. Instead, do proper research before choosing which grape seed extract supplement you wish to buy.

Purpose

You might have a different purpose to use the grape seed extract supplement. Before choosing the grape seed supplement, understand why you want to use it.

It can be used for medicinal purposes, for the betterment of your skin and hair also. The kind of supplement you choose should be able to fulfill your purposes.

Diet type

Vegan diet requirements should also be kept in mind if you are a vegetarian. Dietary requirements should be given importance as you do not want to lose your diet just for the grape seed extract supplements.

Type

What type of grape seed supplement do you want to use? These supplements are available in the form of powder, capsules, and liquid.

You can choose to use any one of them. You get several options to choose the one that meets your comfort level. All the best grape seed extract supplements in Japan featured on our list are available in various types.

 

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Benefits of using grape seed extract supplements

Improve blood flow

Some studies indicate that grape seed extract may improve blood flow. For example, in an 8-week study in 17 healthy postmenopausal women, taking 400 mg of grape seed extract had blood-thinning effects, reducing the risk of blood clots.

An additional study in 8 healthy young women evaluated the effects of a single 400-mg dose of proanthocyanidin from the best grape seed extract supplements in Japan instantly followed by 6 hours of sitting. It helps in relieving leg swelling and edema by 70%, compared with not taking grape seed extract.

Strengthen bone 

Including grape seed extract in your diet with calcium has a significant effect on bone formation and bone strength for the remedy of bone debility caused by a low level of calcium.

Improve kidney function

Your kidneys are particularly sensitive to oxidative damage, which is usually irreversible.

In one study, 23 people having chronic renal failure were given 2 grams of grape seed extract daily for 6 months and then analogised with a placebo group. As a result, urinary protein reduced by 3%, and kidney filtration improved by 9%.

This indicates that the kidneys of those in the test group were much better able to filter urine than the kidneys of those in the placebo group.

Inhibit infectious growth

The best grape seed extract supplements in Japan have antibacterial and antifungal properties. Studies have indicated that grape seed extract inhibits the development of common foodborne bacteria, including Campylobacter and E. coli, which are often responsible for extreme food poisoning and abdominal upset.

In lab studies, grape seed extract deters 43 strains of antibiotic-resistant Staphylococcus aureus bacteria. Candida is a common yeast-like fungus that can often result in candida overgrowth or thrush. The grape seed extract is widely used in traditional medicine as a treatment for candida.

Lower blood pressure

Several studies have examined the effects of grape seed extract on High blood pressure.

A review of 16 studies including 810 people with increased blood pressure or an elevated risk found that consuming 100–2,000 mg of grape seed extract daily notably reduced systolic and diastolic blood pressure by an average of 6.08 mmHg and 2.8 mmHg, respectively.

Those under 50 years of age with obesity or a metabolic disorder demonstrated the best improvements. The most favourable results came from lower doses of 100–800 mg daily for 8–16 weeks, rather than a single dose of 800 mg or more.

Decrease oxidative damage

A high blood level of LDL cholesterol is a comprehended risk factor for heart disease. The oxidation of LDL cholesterol increases this risk and plays a central role in atherosclerosis or the buildup of fatty plaque in your arteries.

In several animal studies, the best grape seed extract supplements in Japan decrease LDL oxidation initiated by high-fat diets. Additionally, some research in humans indicates similar results.

When 8 healthy people ate a high-fat meal, taking 300 mg of grape seed extract inhibited the oxidation of fats in the blood, compared with a 150% growth seen in those who did not take grape seed extract.

Reduce cancer risk

Grape seeds have proanthocyanidins which might control the development of cancer. However, experts believe that the protective characteristic of proanthocyanidins come with different routes.

It helps reduce oxidative stress and immunosuppression by altering cytokine activity. Still, further research is required to firm up the findings.

Heal your wounds

A grape seed extract has the prospect to increase the speed at that wounds heal.

A study “provided firm evidence to support that topical application of GSPE (Grape Seed Proanthocyanidin Extract) illustrates a feasible and productive approach to support skin wound healing.”

Side-effects of using Grape Seed Extract Supplements

The grape seed extract is normally considered safe. However, side effects may involve headaches, itchy scalp, dizziness, and nausea. People allergic to grapes should not consume grape seed extract. If you have a bleeding problem or high blood pressure, consult your doctor before taking the best grape seed extract supplements in Japan.

If you take any regular medicines, talk to your doctor before you start using grape seed extract. It could interact with drugs like blood thinners, NSAID painkillers (like aspirin, Advil, and Aleve), some heart medicines, cancer treatments, and others.

 

There is no firmly specified dose of grape seed extract. Doses between 100-300 milligrams/day have been used in studies and are prescribed in some European countries. No one knows what the highest safe dose is.

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Conclusion

The best grape seed extract supplement in Japan is an excellent supplement made from the seeds of grapes.

It is a rich source of antioxidants, particularly proanthocyanidins. The antioxidants in grape seed extract may help ease inflammation, tissue damage and oxidative stress that occur alongside chronic diseases.

By taking a grape seed extract supplement, you get the opportunity to keep your heart, brain, kidney, liver, and skin health in the best condition.

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Faye James

Clinical Nutritionist

Nutritionist verified

Experienced Senior Content Designer with an impressive portfolio of collaborations with renowned brands such as Woolworths, Weight Watchers, Fitness First, Barry's, Goodlife and Table of Plenty. Accredited Nutritionist and Cook Book Author, with extensive media coverage in ELLE, Glamour, Harpers Bazaar, Daily Express, Telegraph UK, MailOnline, WHIMN, WHO, New Idea, Girlfriend, Practical Parenting, Kidspot, Good Food, Body and Soul, Prevention, Good Health, Healthy Food Guide, Woman's Weekly, Women's Day, NW, Take 5, TV Week, HELLO! and OK! Author of The Menopause Diet (2023), The Long Life Plan (2018) and creator of The 10:10 Diet (2019). Frequently featured as an expert in Body & Soul, and proud member of Nutrition Council Australia and Associate Member of The Australian Menopause Society.