Introduction
The grape seed extract is a dietary supplement created from the seeds of grapes. It is a rich source of antioxidants, particularly proanthocyanidins. The antioxidants in the best grape seed extract supplements in USA may help relieve oxidative stress, inflammation, and tissue injury that can appear alongside chronic diseases.
Most of these health claims are still not supported by credible studies, but some evidence supports their use. The grape seed extract is available as a dietary supplement in a liquid form, tablets, or capsules. Supplements generally contain 50 to 100 milligrams (mg) of grape seed extract.
Studies on animal models have shown that grape seed extract can be beneficial in treating heart disease. Some experts think grape seed extract could even include anticancer and cancer chemopreventive possibilities. Over recent years, there has been a great deal of research suggesting the therapeutic properties of grape seed extract.
Check out our list of the best grape seed extract supplements in USA to find the one you are in search of.
Our pick of the 7 best grape seed extract supplements of 2024 in USA
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Let's take a deep dive into these 7 best Grape Seed Extract Supplements in USA
Best Overall Grape Seed Extract Supplements in USA
NOW
A+
Zotezo review
The NOW Grape Seed Extract, Maximum Strength 500 mg – 90 Veg Capsules is a cost-effective, high-quality product that supports vascular, bone, and kidney health with its highly concentrated formula. While some users may have brand preferences, the easy-to-swallow capsules make it a convenient choice for those looking to incorporate grape seed extract into their health routine.
Product details
Benefits of NOW Grape Seed Extract 500mg ...
Drawbacks
A+
Zotezo review
The Carlyle Grape Seed Extract 24,000 mg is a potent and value-for-money supplement recommended for promoting hair growth and heart health. However, some users may find the large capsules challenging to swallow, and there have been occasional delays in shipping reported by a few customers.
Product details
Benefits of Carlyle Grape Seed Extract 24,00...
Weaknesses
A+
Zotezo review
The Nutricost Grape Seed Extract offers a high-potency formula with 28,000mg of grape seed per serving in a convenient single capsule size. It is non-GMO, gluten-free, and vegetarian-friendly, making it a suitable choice for many consumers. However, individuals with grape seed allergies should exercise caution, and some users may find the capsules too large to swallow comfortably.
Product details
Benefits of Nutricost Grape Seed Extract 28,...
Disadvantages
NOW Sports - Nutrition and Wellness
A+
Zotezo review
The NOW Supplements Grape Seed 100 mg is a highly concentrated and standardized extract rich in polyphenols and Vitamin C, offering effective relief for hayfever and varicose veins. However, its frequent replenishment and potential need for counting capsules may be drawbacks for some users.
Product details
Benefits of NOW Grape Seed Extract with Vita...
Negatives
NBTY.inc - US Nutrition,inc.
A
Zotezo review
Puritan’s Pride Grapeseed Extract 100 Mg, 200 Count” offers a doctor-recommended, natural antioxidant health support option with 100 mg Grapeseed Extract per capsule. While it provides good value for money and is effective for periodontal disease, some users may find its effectiveness limited and it may not be suitable for everyone’s needs.
Product details
Benefits of Puritan’s Pride Grapeseed ...
Cons
Zazzee Naturals
A
Zotezo review
The Zazzee High Strength Grape Seed 50:1 Extract offers a potent 20,000 mg strength per capsule with 95% Polyphenols, making it a high-quality supplement. While it provides a 6-month supply and is Non-GMO, the large capsule size may be challenging for some to swallow, and it could potentially cause mild stomach discomfort in certain users.
Product details
Benefits of Zazzee Grape Seed Extract: High ...
Drawbacks
Nature's Way
B+
Zotezo review
Nature’s Way Premium Extract Grape Seed is a potent antioxidant supplement standardized to 95% polyphenols, offering positive effects on cardiovascular health, eye health, and cognition. Despite a bitter taste when capsules are opened and occasional shipping delays for Prime members, it remains an affordable and convenient option from a trusted brand.
Product details
Benefits of Nature’s Way Grape Seed Ex...
Weaknesses
Tips for choosing the right grape seed extract supplements for you
Dose
Dose forms a critical part while choosing the grape seed extract supplement. Therefore, you need to get a good understanding of how much supplement intake you should do.
It depends on your body conditions and your requirements. For example, pregnant women should avoid taking grape seed supplements.
Brand
Choosing the best brand helps you get the best quality. For example, if you want to use the best grape seed extract supplements in USA, you should keep your faith in the most reputed brand.
Price
Keep in mind that the highest-priced grape seed extract is not always of the best quality. Similarly, the one with the lowest price does not mean that the product is a low-quality one.
So, do not just go with the price. Instead, do proper research before choosing which grape seed extract supplement you wish to buy.
Purpose
You might have a different purpose to use the grape seed extract supplement. Before choosing the grape seed supplement, understand why you want to use it.
It can be used for medicinal purposes, for the betterment of your skin and hair also. The kind of supplement you choose should be able to fulfill your purposes.
Diet type
Vegan diet requirements should also be kept in mind if you are a vegetarian. Dietary requirements should be given importance as you do not want to lose your diet just for the grape seed extract supplements.
Type
What type of grape seed supplement do you want to use? These supplements are available in the form of powder, capsules, and liquid.
You can choose to use any one of them. You get several options to choose the one that meets your comfort level. All the best grape seed extract supplements in USA featured on our list are available in various types.
Products listed here are carefully reviewed and tested by our expert authors and reviewers. If you buy through links on this page, we may earn a small commission. Here’s our editorial process.
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Benefits of using grape seed extract supplements
Improve blood flow
Some studies indicate that grape seed extract may improve blood flow. For example, in an 8-week study in 17 healthy postmenopausal women, taking 400 mg of grape seed extract had blood-thinning effects, reducing the risk of blood clots.
An additional study in 8 healthy young women evaluated the effects of a single 400-mg dose of proanthocyanidin from the best grape seed extract supplements in USA instantly followed by 6 hours of sitting. It helps in relieving leg swelling and edema by 70%, compared with not taking grape seed extract.
Strengthen bone
Including grape seed extract in your diet with calcium has a significant effect on bone formation and bone strength for the remedy of bone debility caused by a low level of calcium.
Improve kidney function
Your kidneys are particularly sensitive to oxidative damage, which is usually irreversible.
In one study, 23 people having chronic renal failure were given 2 grams of grape seed extract daily for 6 months and then analogised with a placebo group. As a result, urinary protein reduced by 3%, and kidney filtration improved by 9%.
This indicates that the kidneys of those in the test group were much better able to filter urine than the kidneys of those in the placebo group.
Inhibit infectious growth
The best grape seed extract supplements in USA have antibacterial and antifungal properties. Studies have indicated that grape seed extract inhibits the development of common foodborne bacteria, including Campylobacter and E. coli, which are often responsible for extreme food poisoning and abdominal upset.
In lab studies, grape seed extract deters 43 strains of antibiotic-resistant Staphylococcus aureus bacteria. Candida is a common yeast-like fungus that can often result in candida overgrowth or thrush. The grape seed extract is widely used in traditional medicine as a treatment for candida.
Lower blood pressure
Several studies have examined the effects of grape seed extract on High blood pressure.
A review of 16 studies including 810 people with increased blood pressure or an elevated risk found that consuming 100–2,000 mg of grape seed extract daily notably reduced systolic and diastolic blood pressure by an average of 6.08 mmHg and 2.8 mmHg, respectively.
Those under 50 years of age with obesity or a metabolic disorder demonstrated the best improvements. The most favourable results came from lower doses of 100–800 mg daily for 8–16 weeks, rather than a single dose of 800 mg or more.
Decrease oxidative damage
A high blood level of LDL cholesterol is a comprehended risk factor for heart disease. The oxidation of LDL cholesterol increases this risk and plays a central role in atherosclerosis or the buildup of fatty plaque in your arteries.
In several animal studies, the best grape seed extract supplements in USA decrease LDL oxidation initiated by high-fat diets. Additionally, some research in humans indicates similar results.
When 8 healthy people ate a high-fat meal, taking 300 mg of grape seed extract inhibited the oxidation of fats in the blood, compared with a 150% growth seen in those who did not take grape seed extract.
Reduce cancer risk
Grape seeds have proanthocyanidins which might control the development of cancer. However, experts believe that the protective characteristic of proanthocyanidins come with different routes.
It helps reduce oxidative stress and immunosuppression by altering cytokine activity. Still, further research is required to firm up the findings.
Heal your wounds
A grape seed extract has the prospect to increase the speed at that wounds heal.
A study “provided firm evidence to support that topical application of GSPE (Grape Seed Proanthocyanidin Extract) illustrates a feasible and productive approach to support skin wound healing.”
Side-effects of using Grape Seed Extract Supplements
The grape seed extract is normally considered safe. However, side effects may involve headaches, itchy scalp, dizziness, and nausea. People allergic to grapes should not consume grape seed extract. If you have a bleeding problem or high blood pressure, consult your doctor before taking the best grape seed extract supplements in USA.
If you take any regular medicines, talk to your doctor before you start using grape seed extract. It could interact with drugs like blood thinners, NSAID painkillers (like aspirin, Advil, and Aleve), some heart medicines, cancer treatments, and others.
Recommended Dosage of Grape Seed Extract Supplements
There is no firmly specified dose of grape seed extract. Doses between 100-300 milligrams/day have been used in studies and are prescribed in some European countries. No one knows what the highest safe dose is.
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Conclusion
The best grape seed extract supplement in USA is an excellent supplement made from the seeds of grapes.
It is a rich source of antioxidants, particularly proanthocyanidins. The antioxidants in grape seed extract may help ease inflammation, tissue damage and oxidative stress that occur alongside chronic diseases.
By taking a grape seed extract supplement, you get the opportunity to keep your heart, brain, kidney, liver, and skin health in the best condition.
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Experienced Senior Content Designer with an impressive portfolio of collaborations with renowned brands such as Woolworths, Weight Watchers, Fitness First, Barry's, Goodlife and Table of Plenty. Accredited Nutritionist and Cook Book Author, with extensive media coverage in ELLE, Glamour, Harpers Bazaar, Daily Express, Telegraph UK, MailOnline, WHIMN, WHO, New Idea, Girlfriend, Practical Parenting, Kidspot, Good Food, Body and Soul, Prevention, Good Health, Healthy Food Guide, Woman's Weekly, Women's Day, NW, Take 5, TV Week, HELLO! and OK! Author of The Menopause Diet (2023), The Long Life Plan (2018) and creator of The 10:10 Diet (2019). Frequently featured as an expert in Body & Soul, and proud member of Nutrition Council Australia and Associate Member of The Australian Menopause Society.
