Introduction

Urolithin A, the natural compound that has been making waves in the health and wellness community! If you’re reading this article, chances are you’re already familiar with the potential benefits of Urolithin A and are on the hunt for the best supplements to incorporate into your daily routine. Well, you’ve come to the right place.

Urolithin A is a metabolite produced by our bodies when we consume foods rich in ellagitannins, which are compounds found in certain fruits like pomegranates, strawberries, and raspberries. Research has shown that Urolithin A may have a range of health benefits, from supporting muscle health to promoting longevity by enhancing cellular recycling processes known as autophagy. This natural compound has certainly piqued the interest of many health enthusiasts and researchers alike.

In this article, we’ll dive deep into the best Urolithin A supplements in USA. We’ll explore what Urolithin A is, its potential health benefits, and most importantly, we’ll guide you through the selection process to help you find the best Urolithin A supplements available on the market today. Whether you’re looking to enhance your workout performance, boost your overall well-being, or simply curious about the potential of this remarkable compound, we’ve got you covered. Let’s embark on this journey of discovery together!

Urolithin A Supplements in USA

Our pick of the 6 best Urolithin A of 2024 in USA

Let's take a deep dive into these 6 best Urolithin A Supplements in USA

Best Overall Urolithin A Supplements in USA

Nutriissa

6

Nutriissa Urolithin A –  1000mg per Serving

A

Zotezo review

Nutriissa, Muscle Health and Performance: Studies suggest that Urolithin-A can enhance muscle function and promote muscle growth. It may activate molecular pathways involved in muscle protein synthesis and improve muscle endurance, making it potentially beneficial for athletes and individuals looking to enhance their physical performance. Go Further & Last Longer : Anti-Inflammatory Effects: Urolithin-A possesses anti-inflammatory properties, which may help reduce inflammation in the body. Less inflammation in the body means quicker recovery times for stressed and strained areas.

Product details

  • Pack Size: 0.12 Kilograms- [120 Softgels]

  • Form: Softgel

  • Certification: N.A

Benefits of Nutriissa Urolithin A – 1...

  • Anti-Aging Properties, Anti-Inflammatory Effects, Urolithin-A is highly studied by scientists and longevity experts., Premium Quality Cellular Health Support.

Best Urolithin A Supplements Runner Up in USA

Timeline

1

Mitopure Urolithin A Supplement – First Clinically Tested Highly Pure Urolithin A

A

Zotezo review

Timeline , Mitopure has demonstrated its capacity to enhance mitochondrial well-being, delivering notable outcomes such as a remarkable 12% increase in muscle strength within just 16 weeks and an impressive 15% boost in endurance after only 8 weeks, in comparison to a placebo. The suggested daily dosage ranges from 500mg (equivalent to 2 softgels) to 1000mg (4 softgels).

Product details

  • Pack Size: 0.47 Kilograms - 60 count

  • Form: Softgel

  • Certification: N.A

Benefits of Mitopure Urolithin A Supplement ...

  • This power-supplement delivers 6X more Urolithin A than a glass of pomegranate juice, without any of the sugar, Anti-Aging, Energy and Muscle Strength.

Weaknesses

  • The capsules came all stuck together.

B+

Zotezo review

Nature’s Fusions, Urolithin A supplement is made with high-quality ingredients to ensure optimal potency and effectiveness. We prioritize purity, potency, and safety, adhering to strict quality control standards in our manufacturing process. A Powder is encapsulated in easy to swallow Vegan capsules for your convenience. Each bottle contains 30 capsules, providing a 15-day supply of our Urolithin A Supplement. With the recommended daily dosage of 2 capsules, it’s easy to incorporate into your daily routine.

Product details

  • Pack Size: 0.03 Kilograms - 30 count

  • Form: Capsule

  • Certification: GMP

Benefits of Nutri Urolithin A Supplement 500...

  • 3rd Party Tested, Pomegranate Supplement, Antioxidant, Cell Repair.

0

Neurogan High-Potency Urolithin A Capsules

B

Zotezo review

Neurogan ,Urolithin A is like fuel for your cells. By supporting efficient energy production, Urolithin A may encourage cellular vitality and overall well-being, making it an ideal choice for those seeking to optimize their health. By supporting energy and muscle recovery, Urolithin A may help you push your limits and achieve your fitness goals.

Product details

  • Pack Size: 0.07 Kilograms - 60 count

  • Form: Capsule

  • Certification: N.A

Benefits of Neurogan High-Potency Urolithin ...

  • Crafted with the utmost care,Money back guarantee, Health Support, Pomegranate flavour.

Best High Dose Urolithin A Supplements in USA

Pepeior

C+

Zotezo review

Pepeior , Mitochondrial dysfunction is a recognized hallmark of aging. Urolithin A, however, can recycles aging and dysfunctional mitochondria into more efficient, vital, or stronger mitochondria,plays a crucial role in muscle tissue and longevity issues. If longevity is your goal, our supplement is tailored to fulfill your aspiration.

Product details

  • Pack Size:120.00 Count

  • Form: Softgel

  • Certification: N.A

Benefits of Pepeior Urolithin A Supplement 2...

  • Energy & Muscle, Longevity, Non-Gmo, Overall Wellness.

Best Urolithin A Supplements Powder in USA

Maxlife Naturals

C+

Zotezo review

Maxlife Naturals, ProMito Urolithin A targets health at the mitochondrial level by promoting mitophagy (cellular health rejuvenation) activation within the cell. Cellular health is further assisted by Urolithin A anti-inflammatory effects throughout the body and may activate longevity pathways, AMPK and SIRT1, associated with metabolic health and increased lifespan.

Product details

  • Pack Size: 28.00 Count

  • Form: Capsule

  • Certification: cGMP

Benefits of Maxlife Naturals ProMito –...

  • Cell Repair,Cellular Health Support ,Alternative to NMN, NAD, CoQ10, Resveratrol, PQQ for Healthy Aging.

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Nutritional facts of Urolithin A

Nutrient Amount Per Serving
Urolithin A Varies by product, typically 250mg – 500mg
Calories 2-4 kcal (negligible)
Protein Negligible
Carbohydrates Negligible
Fat Negligible
Fiber Negligible

Tips for choosing the right Urolithin A for you

If you’re considering adding Urolithin A supplements to your daily wellness routine, you’re on the right track to potentially reap a host of health benefits. However, navigating the world of dietary supplements can be a daunting task, given the multitude of options available. To help you make an informed decision, we’ve put together this buyer’s guide to assist you in selecting the best Urolithin A supplement for your specific needs.

1. Research and Choose Reputable Brands

When it comes to dietary supplements, not all brands are created equal. To ensure the safety and efficacy of your Urolithin A supplement, prioritize products from well-established and reputable manufacturers. Look for brands that:

  • Conduct third-party testing: This ensures that the product’s label accurately reflects its contents and that it meets quality and safety standards.
  • Have a transparent and informative website: A reputable brand will provide detailed information about their products, including the source of Urolithin A, dosage recommendations, and potential side effects.
  • Are endorsed by healthcare professionals: Some brands collaborate with healthcare experts who can vouch for the quality and effectiveness of their products.

2. Check the Urolithin A Source

The source of Urolithin A in supplements matters. While this compound naturally occurs in foods like pomegranates, strawberries, and raspberries, supplements can derive Urolithin A from different sources, such as ellagic acid or synthetic production. Look for supplements that explicitly state the source of their Urolithin A, and consider the following:

Natural Sources: Urolithin A derived from natural food sources may be preferred by those who prefer a more whole-food approach to supplementation. Natural sources are often considered safe and well-tolerated.

Ellagic Acid Conversion: Some supplements provide ellagic acid, a precursor to Urolithin A, with the expectation that your body will convert it into Urolithin A. While this can be effective for some individuals, it may not be as direct or predictable as taking Urolithin A directly.

Synthetic Urolithin A: Synthetic Urolithin A is created in a laboratory setting. While it can be a pure and standardized form, some individuals prefer natural sources due to potential concerns about synthetic compounds.

3. Consider the Dosage

Dosage can vary significantly between Urolithin A supplements. The recommended daily dosage generally ranges from 250mg to 500mg. When choosing a supplement, take the following factors into account:

Your Health Goals: Your dosage may depend on your specific health objectives. For instance, if you’re aiming for muscle support or enhanced athletic performance, you might lean toward the higher end of the dosage range. Conversely, if you’re primarily interested in cellular health, a lower dose may suffice.

Starting Conservatively: If you’re new to Urolithin A supplementation, it’s a good idea to start with a lower dose and gradually increase it over time. This allows your body to adapt and helps you assess your tolerance.

4. Check for Additional Ingredients

Urolithin A supplements may come with added ingredients that can enhance their effectiveness or serve specific purposes. Some common additives include:

Bioavailability Enhancers: These ingredients, such as black pepper extract (piperine) or liposomal delivery systems, can improve the absorption and bioavailability of Urolithin A, potentially making the supplement more effective.

Antioxidants: Some supplements include additional antioxidants like vitamin C or vitamin E to complement Urolithin A’s antioxidant properties. This can provide a synergistic effect for cellular protection.

Anti-Inflammatory Compounds: Ingredients like curcumin or omega-3 fatty acids may be added to support Urolithin A’s anti-inflammatory benefits.

Digestive Aids: To mitigate potential gastrointestinal discomfort, some supplements include digestive enzymes or probiotics to promote gut health.

It’s important to assess whether these additional ingredients align with your health goals and whether you have any sensitivities or allergies to them.

5. Read User Reviews and Seek Recommendations

User reviews and recommendations from individuals who have used Urolithin A supplements can offer valuable insights. Look for feedback on the product’s effectiveness, side effects, and overall satisfaction. However, keep in mind that individual experiences can vary, so consider a range of perspectives.

6. Assess the Cost and Value

The price of Urolithin A supplements can vary widely depending on the brand, dosage, and additional ingredients. While it’s tempting to choose the most affordable option, consider the overall value, taking into account factors like dosage, quality, and reputation. Sometimes, a slightly higher-priced product may offer better quality and efficacy.

7. Monitor Your Body’s Response

Once you’ve chosen a Urolithin A supplement and incorporated it into your routine, pay close attention to how your body responds. Look for any side effects, improvements in your health goals, or changes in your overall well-being. It may take some time for the effects to become noticeable, so be patient and consistent in your supplementation.

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Benefits of using Urolithin A

Urolithin A supplements have garnered significant attention in recent times due to their amazing health benefits. These remarkable compounds, derived from the natural breakdown of ellagitannins found in certain fruits, offer a range of advantages that have captured the interest of health-conscious individuals. In this section, we’ll delve into the exciting benefits of Urolithin A supplementation, helping you understand why these supplements have gained such popularity.

1. Enhanced Muscle Health:

One of the most talked-about benefits of Urolithin A is its potential to support muscle health. As we age, our muscles naturally experience a decline in mass and function. Urolithin A, however, may help counteract this process by promoting the growth of new, healthy mitochondria—the energy powerhouses of our cells. This mitochondrial rejuvenation can lead to improved muscle strength and endurance, making it an appealing option for athletes and fitness enthusiasts looking to optimize their performance.

2. Boosted Cellular Autophagy:

Cellular autophagy is the body’s way of cleaning house, eliminating damaged or dysfunctional cellular components. Urolithin A has been shown to enhance this process, facilitating the removal of cellular debris and potentially reducing the risk of age-related diseases. By supporting autophagy, Urolithin A may contribute to overall cellular health, which is crucial for maintaining optimal bodily function.

3. Anti-Inflammatory Properties:

Chronic inflammation is at the root of many health issues, from arthritis to heart disease. Urolithin A’s anti-inflammatory properties can help mitigate this risk. By reducing inflammation, it may support joint health and decrease the likelihood of developing inflammatory conditions. Incorporating Urolithin A into your daily routine may help you maintain a more active, pain-free lifestyle.

4. Antioxidant Protection:

Free radicals, those pesky molecules that can damage cells and contribute to aging, are kept in check by antioxidants. Urolithin A acts as a potent antioxidant, scavenging free radicals and protecting your cells from oxidative stress. This antioxidant prowess not only promotes healthy aging but may also reduce the risk of chronic diseases associated with oxidative damage.

5. Cardiovascular Support:

Maintaining heart health is a top priority for many, and Urolithin A may play a role in achieving this goal. Some studies suggest that Urolithin A can help regulate blood pressure, improve blood vessel function, and reduce the risk of cardiovascular diseases like hypertension and atherosclerosis. These heart-protective benefits make Urolithin A a valuable addition to your supplement regimen.

6. Gut Health and Microbiome Balance:

The gut microbiome has a profound impact on our overall well-being, from digestion to immunity. Urolithin A may promote a healthy gut by encouraging the growth of beneficial bacteria while suppressing harmful ones. This balance in the gut microbiome can lead to improved digestion, better nutrient absorption, and enhanced immune function.

7. Longevity and Aging Gracefully:

Who doesn’t want to age gracefully? Urolithin A has garnered attention for its potential role in extending lifespan by promoting cellular health and reducing the burden of age-related diseases. While research in this area is still evolving, the longevity potential of Urolithin A is undoubtedly exciting.

8. Cognitive Support:

Emerging research suggests that Urolithin A may also benefit brain health. By enhancing cellular autophagy, reducing inflammation, and protecting against oxidative stress, it may contribute to cognitive function and memory retention. This makes Urolithin A a promising candidate for those looking to maintain mental sharpness as they age.

9. Metabolic Health:

Urolithin A may have a positive impact on metabolic health, potentially aiding in the management of conditions like obesity and type 2 diabetes. Some studies suggest that it can help regulate blood sugar levels and improve insulin sensitivity, making it a valuable tool for individuals looking to maintain a healthy weight and prevent metabolic disorders.

10. Skin Health:

Last but not least, Urolithin A’s antioxidant properties may extend to the skin, where it can help combat the signs of aging, such as wrinkles and fine lines. By protecting skin cells from damage, it contributes to a youthful, radiant complexion.

While these benefits are promising, it’s important to note that research on Urolithin A is still relatively new, and more studies are needed to confirm its full range of effects and optimal dosages. As with any supplement, it’s wise to consult with a healthcare professional before adding Urolithin A to your daily routine, especially if you have underlying health conditions or are taking medications. Nevertheless, the potential benefits of Urolithin A are certainly intriguing, and as the research continues to unfold, it may become a valuable addition to your wellness regimen.

benefits of urolithin A supplements

Side-effects of using Urolithin A Supplements

While Urolithin A supplements offer a promising array of potential health benefits, it’s essential to be aware of possible side effects and considerations when incorporating them into your daily routine. As with any dietary supplement, individual reactions can vary, and it’s advisable to exercise caution and consult with a healthcare professional before starting Urolithin A supplementation. In this section, we’ll explore some of the side effects and considerations associated with Urolithin A.

1. Gastrointestinal Distress:

Some individuals may experience gastrointestinal discomfort when taking Urolithin A supplements. This can include symptoms like bloating, gas, diarrhea, or stomach cramps. If you have a sensitive stomach or a history of digestive issues, it’s essential to start with a lower dose and gradually increase it to assess your tolerance. Additionally, taking Urolithin A with food may help reduce the risk of digestive upset.

2. Interactions with Medications:

Urolithin A’s effects on drug metabolism are not fully understood. If you are currently taking medications, particularly those that rely on specific metabolic pathways in the liver, consult with your healthcare provider before adding Urolithin A supplements to your regimen. There may be potential interactions that could affect the efficacy or safety of your medications.

3. Allergic Reactions:

Although rare, allergic reactions to Urolithin A supplements can occur. If you have a known allergy to pomegranates, berries, or any foods rich in ellagitannins, exercise caution when using Urolithin A supplements. Look for signs of an allergic reaction, such as itching, hives, swelling, or difficulty breathing, and discontinue use if any of these symptoms occur.

4. Dosage and Timing:

Determining the appropriate dosage of Urolithin A can be challenging. While research is ongoing, there is no established recommended daily allowance (RDA) for Urolithin A supplementation. Overdosing or taking excessive amounts may increase the risk of side effects. Start with the manufacturer’s recommended dosage and monitor your body’s response. More is not necessarily better, and moderation is key.

5. Limited Long-Term Data:

While initial studies on Urolithin A’s benefits are promising, there is limited long-term data on its safety. As a result, it’s crucial to use these supplements cautiously and avoid extended use until more research is conducted to determine their long-term effects.

6. Purity and Quality:

The quality of Urolithin A supplements can vary among brands. To minimize potential side effects, opt for products from reputable manufacturers that undergo third-party testing for purity and quality. These products are more likely to contain the specified amount of Urolithin A and fewer impurities.

7. Individual Variations:

Keep in mind that individual responses to Urolithin A may differ. While some people may experience no side effects and enjoy the benefits, others may be more sensitive or react differently. Pay close attention to how your body responds and consult with a healthcare professional if you have any concerns.

Determining the right dosage of Urolithin A supplements can be a bit of a puzzle, as the research in this area is still evolving. The optimal dosage can depend on various factors, including your age, overall health, and the specific goals you hope to achieve with Urolithin A supplementation. Here, we’ll provide some general guidelines to help you navigate the dosage landscape.

1. Start Low and Go Slow:

When beginning any new supplement regimen, it’s wise to start with a lower dose and gradually increase it over time. This approach allows your body to adjust and helps you monitor for any potential side effects. For Urolithin A, a typical starting dose ranges from 250mg to 500mg per day.

2. Consult with a Healthcare Professional:

Before incorporating Urolithin A supplements into your routine, especially if you have underlying health conditions or are taking medications, consult with a healthcare professional. They can provide personalized recommendations based on your specific health needs and potential interactions with other medications or supplements you may be taking.

3. Consider Your Goals:

The dosage of Urolithin A may vary depending on your health and fitness goals. If you’re primarily interested in the potential muscle-enhancing benefits, you might opt for a higher dosage within the recommended range. On the other hand, if you’re aiming to support general wellness and cellular health, a lower dose may suffice.

4. **Pay Attention to Product Labels**: Different Urolithin A supplements on the market may have varying concentrations of the active compound. Be sure to read product labels carefully to determine the exact dosage provided per serving. Some supplements may offer capsules or powders with different dosing options.

5. Monitor Your Body’s Response:

Once you start taking Urolithin A supplements, pay close attention to how your body responds. This includes monitoring for any side effects, such as gastrointestinal discomfort, allergic reactions, or other adverse effects. If you experience any negative effects, discontinue use and consult with a healthcare professional.

6. Duration of Use:

While Urolithin A is generally considered safe for short-term use, there is limited information available regarding its long-term safety. It’s advisable to use Urolithin A supplements intermittently rather than continuously until more long-term research becomes available.

7. Complement with Diet:

Remember that Urolithin A is a natural compound found in certain foods like pomegranates, strawberries, and raspberries. You can complement your Urolithin A supplementation with a diet rich in these foods to naturally boost your intake of this compound. However, keep in mind that the levels of Urolithin A in these foods can vary widely.

Source: NMN.com

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Frequently asked questions on Urolithin A

1. What is Urolithin A?

2. How should I take Urolithin A supplements?

3. Who should not take Urolithin A supplements?

4. Are Urolithin A supplements FDA-approved?

5. How are Urolithin A supplements made?

Sum it up

Here's the list of the 6 best Urolithin A Supplements of 2024 in USA

  1. Best High Dose Urolithin A Supplements:
  2. Best Urolithin A Supplements Powder:

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Conclusion

Urolithin A is a type of phytonutrient produced by ellagitannins’ metabolism. This compound has been shown to have many potential health benefits, including preventing or improving conditions like Parkinson’s disease, Alzheimer’s disease, heart disease, and cancer. While more research is needed to confirm these effects, urolithin A supplements may be a promising way to improve your health. If you’re looking for a urolithin A supplement, choose one that is high quality and free of contaminants.

In conclusion, the world of Urolithin A supplements holds remarkable promise for those seeking to enhance their health and well-being. From muscle support and cellular rejuvenation to potential longevity benefits, Urolithin A has piqued the interest of health enthusiasts and researchers alike.

As you embark on your journey to find the best Urolithin A supplement for your needs, remember the key takeaways from this article. Choose reputable brands that prioritize transparency and quality, consider the source of Urolithin A, tailor the dosage to your health goals, and consult with a healthcare professional for personalized guidance. Keep an eye out for additional ingredients that align with your objectives, and monitor your body’s response diligently.

Ultimately, the effectiveness of Urolithin A supplements can vary from person to person. What matters most is your individual experience and the impact these supplements have on your overall health and vitality.

We hope this guide has been informative and helpful in your quest to make an informed choice. If you have any feedback or questions, we’d love to hear from you. Your insights are invaluable as we strive to provide you with the most up-to-date and relevant information on dietary supplements. Please share your thoughts, and let us know how we can continue to assist you on your path to better health.

avatar
Dt. Stacy Gulbin

RD, M.Ed., MS

Dietitian verified

Stacy has been a registered dietitian since 2010, She is currently working as an author, and clinical dietitian at Zotezo. She has experience in various fields of nutrition including research, fitness, medical weight loss, long-term care, rehab, and bariatrics. She has also been contributing to various online entities since 2011 including Examiner.com, Livestrong, and Cdiabetes.com