Introduction
Pyridoxine, or vitamin B6, is one of the eight B vitamins, and it is a water-soluble vitamin that may be found in many foods naturally and in meals and supplements. The components in this family of essential vitamins are required for vital body functions.
The active coenzyme form (pyridoxal 5 phosphate) is the most used marker of B6 blood levels. PLP is a coenzyme that helps over 100 enzymes accomplish various tasks, including protein, carbohydrate, and fat breakdown. Besides supporting immunological function and brain health, it helps maintain normal homocysteine levels (because high amounts can cause cardiac problems.)
The deficiency of B6 can be very harmful to our bodies. To save you from any such problem and help you get your hands on the best product, we have included a list of top 8 best Vitamin B6 supplements in USA and a buying guide in this article. So, give it a good read.
Our pick of the 8 best vitamin B6 supplements of 2024 in USA
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Let's take a deep dive into these 8 best Vitamin B6 Supplements in USA
Best Overall Vitamin B6 Supplements in USA
Pharmavite
A+
Zotezo review
The Nature Made Vitamin B6 100 mg supplement is a trusted product that supports energy metabolism and the production of neurotransmitters. While some users may find the tablets too large to swallow comfortably, overall it offers good value for the money with a 100-day supply in one bottle.
Product details
Benefits of Nature Made B6 100mg Energy Support
Drawbacks
Natures Craft
A+
Zotezo review
The Potent Vitamin B6 Gummies for Adults offer a delicious and easy-to-take option for individuals looking to boost their immune, nerve, and mood support. While the vegan and kosher gummies provide energy and focus, some users may find the 30-count pack size limiting and prefer a larger quantity for convenience.
Product details
Benefits of Vegan B6 Gummies for Immune Support
Weaknesses
Horbäach
A+
Zotezo review
The P-5-P Activated Vitamin B6 100mg by Horbaach is a professional-grade supplement offering the metabolically active form of Vitamin B-6 in a vegetarian formula. While expertly crafted and committed to purity, users should be cautious with dosage timing and start with half a pill due to potential sleep disturbances.
Product details
Benefits of Horbaach P-5-P Vitamin B6 Tablets
Disadvantages
Nature's Bounty
A+
Zotezo review
Nature’s Bounty Vitamin B6 tablets are an effective way to support energy metabolism and promote nervous system health with easy-to-swallow 100mg tablets. While the product lacks an unpleasant flavor, it may not be ideal for individuals sensitive to taste due to an unpleasant taste when chewed.
Product details
Benefits of Nature’s Bounty B6 100mg T...
Negatives
Bronson Labs
A+
Zotezo review
The Vitamin B6 100 mg Premium Supplement is a superior quality product that supports protein metabolism, immune function, energy metabolism, neurotransmitter synthesis, cardiovascular health, red blood cell production, and hormone regulation. However, users should be cautious of potential interactions with medications.
Product details
Benefits of B6 100 mg Premium Supplement 250...
Cons
Nature's Way
A+
Zotezo review
Nature’s Way Vitamin B-6 Supplement provides excellent cellular energy support and helps with amino acid and protein metabolism. It is easy to swallow, affordable, and supports migraine relief. However, it may not be suitable for children under 12 and users may need to consult a doctor before use.
Product details
Benefits of Nature’s Way B-6 Supplemen...
Drawbacks
NOW Sports - Nutrition and Wellness
A
Zotezo review
The NOW Supplements Vitamin B-6 (Pyridoxine HCl) offers cardiovascular health support, nervous system function, and healthy homocysteine metabolism in an affordable and reputable package. While the 100 mg dosage may be excessive for some users and lacks clear warnings about potential toxicity risks, its easy-to-swallow formulation makes it a trustworthy choice for many.
Product details
Benefits of NOW Vitamin B-6 100mg Veg Capsules
Weaknesses
Nutricost
A
Zotezo review
The Nutricost Vitamin B6 (Pyridoxine HCl) 100mg, 240 Capsules product offers a clear and certified option for those seeking a non-GMO and gluten-free Vitamin B6 supplement. While easy to swallow for most, individuals with sensitivities to Pyridoxine HCl may need to consider other options due to the size of the capsules.
Product details
Benefits of Nutricost Vitamin B6 Capsules, 1...
Disadvantages
Tips for choosing the right vitamin B6 supplements for you
Before buying the best Vitamin B6 supplements in USA, consider certain factors.
Type
The type of nutrient utilized in manufacturing is the first aspect to examine before selecting the best vitamin B6. Vitamin B6 is present in food in three primary forms, each of which can be classed according to its active principle:
- Pyridoxine is a B vitamin found primarily in vegetables and nutritional supplements.
- Pyridoxal is found in animal-based diets. This kind is commonly referred to as P-5-P in supplements (Pyridoxal-5-Phosphate).
- Pyridoxamine is found in animal-based diets.
When looking for a vitamin B6 supplement, look for products containing both Pyridoxine and P-5-P.
You will need your doctor’s help to make the best decision. This is because they all have the same indications for use; the active components are different.
Certified
It is critical to conduct research before purchasing a product off the shelf. Choose companies who test their products independently to ensure quality and potency. If you have allergies, double-check that the label is devoid of the allergen you are allergic to.
Search for a product with a certified non-GMO or USDA Organic logo for the best ingredient integrity. Consumers can also check for quality by going to websites like ConsumerLab, which tests and reviews products independently.
Ingredient list
Before purchasing the best Vitamin B6 supplements in USA, it is critical to check the composition of the vitamin. You can opt for a supplement consisting of only the vitamin and no other ingredients in this situation. The most popular method is to look for vitamin complexes that contain B6 along with other vitamins.
In general, B6 is found in combination with magnesium and zinc. This combo will improve athletes’ strength performance, metabolism, muscle mass repair and construction, and hormone production. However, you should be aware that alternative combinations are available. Each has its own set of advantages for certain types of needs and objectives.
Form
Furthermore, we recommend that you examine what form of supplements suits you. In general, you have the option of taking supplements in the form of capsules or liquids.
It’s vital to consider both the supplement’s practicality and its convenience of use. It’s not uncommon for older adults’s vitamin digestion to be aided by taking it in liquid form, in the form of drops. Although, on the market, this version is more difficult to get by. However, in the case of vitamin B6 pills, dose accuracy is unquestionably higher.
Quantity
Finally, we recommend that you calculate the quantity in either capsules or milliliters. This evaluation should take into account your average prescription for the duration of the supplement’s administration. B6 is typically found in bottles with several capsules ranging from 40 to 250. When it comes to liquid vitamin B6, containers from 30ml to 60ml are available.
Value for money
We don’t recommend paying a lot of money for a Vitamin B6 level supplement. Many good-quality supplements are available on the market at relatively low prices. These lower-dose supplements will give you far more benefits than high-dose supplements, which might harm your health.
Products listed here are carefully reviewed and tested by our expert authors and reviewers. If you buy through links on this page, we may earn a small commission. Here’s our editorial process.
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Benefits of using vitamin B6 supplements
There are several benefits of taking the best vitamin B6 supplements in USA.
Better Circulation
Homocysteine is one of your body’s 21 amino acids. Homocysteine levels in the bloodstream can cause heart issues. Vitamin B6 aids in the maintenance of a healthy level of this amino acid in your blood.
Powerful immune system
Vitamin B6 helps chemical reactions in the immune system, allowing it to work more effectively. Vitamin B6-rich foods will help your body defend against infection. Low levels of vitamin B6 cause a poor immunological response in older persons in studies.
Less morning sickness
Vitamin B6 supplementation has been shown in studies to help with nausea and vomiting during pregnancy.
Better Mood
Vitamin B6 helps in the production of serotonin, a mood-enhancing hormone. According to research, not getting enough vitamin B6 in your diet can lead to depression.
Help relieve PMS symptoms
There is evidence that taking the best vitamin B6 supplement in USA can help alleviate some of the symptoms of premenstrual syndrome, including:
- soreness in the breasts
- Depression
- Anxiety
Reduce the risk of cancer
Maintaining good vitamin B6 levels in your blood may also assist in minimizing your cancer risk. If you already have cancer, vitamin B6 reduces tumor growth in studies.
Improve mental performance
Homocysteine levels above a certain threshold have been linked to dementia, Alzheimer’s, and cognitive decline. Vitamin B6 aids in the regulation of homocysteine levels in the blood.
Side-effects of using Vitamin B6 Supplements
The best Vitamin B6 supplements in USA are probably safe when taken correctly. Vitamin B6 in quantities of 100 mg or less per day is safe. When used in doses of 101-200 mg daily, vitamin B6 may be considered safe. Vitamin B6 can cause stomach pain, nausea, loss of appetite, headaches, and other side effects in some people.
When consumed in dosages of 500 mg or more per day, vitamin B6 may be dangerous. Vitamin B6 in high amounts, especially 1000 mg or more per day, might cause brain and nerve disorders.
Precautions
Certain people should always consult their doctors before including any supplements in their diet. The list includes:
- Pregnant women
- Breastfeeding women
- Patient after weight loss surgery.
- Post-surgical stent placement.
Recommended Dosage of Vitamin B6 Supplements
Here are recommended dosages of Vitamin B6 in your daily diet.
- Newborn to 6 months: 0.1 mg
- Infants 7 months to 1 year: 0.3 mg
- Children 1 to 3 years: 0.5 mg
- Children 4 to 8 years: 0.6 mg
- Children 9 to 13 years: 1 mg
- Boys 14 to 18 years: 1.3 mg
- Girls 14 to 18 years: 1.2 mg
- Men and women 19 to 50 years: 1.3 mg
- Men 51 years and older: 1.7 mg
- Women 51 years and older: 1.5 mg
- Pregnant women: 1.9 mg
- Breastfeeding women: 2 mg
When we include any supplements in our diet, the product mentions the dosage. Follow the instructions and do not overdose. If you still have any problems consult your doctor.
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Conclusion
Hopefully, you have found the one you need on our list of top 8 best Vitamin B6 supplements in USA. When it comes to B6, it is available in many foods as a natural vitamin. Try to include food rich in vitamin B6 in your diet. If for any reason, you cannot, then it’s prudent to buy the best Vitamin B6 supplements on the market.
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Experienced Senior Content Designer with an impressive portfolio of collaborations with renowned brands such as Woolworths, Weight Watchers, Fitness First, Barry's, Goodlife and Table of Plenty. Accredited Nutritionist and Cook Book Author, with extensive media coverage in ELLE, Glamour, Harpers Bazaar, Daily Express, Telegraph UK, MailOnline, WHIMN, WHO, New Idea, Girlfriend, Practical Parenting, Kidspot, Good Food, Body and Soul, Prevention, Good Health, Healthy Food Guide, Woman's Weekly, Women's Day, NW, Take 5, TV Week, HELLO! and OK! Author of The Menopause Diet (2023), The Long Life Plan (2018) and creator of The 10:10 Diet (2019). Frequently featured as an expert in Body & Soul, and proud member of Nutrition Council Australia and Associate Member of The Australian Menopause Society.
